UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF
THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported): March 11, 2004

Shire Pharmaceuticals Group plc

(Exact name of registrant as specified in its charter)

England and Wales

(State or other jurisdiction of incorporation)

0-29630	98-0359573
(Commission File Number)	(I.R.S. Employer Identification No.)

Hampshire International Business Park, Chineham, Basingstoke, Hampshire RG24 8EP England
(Address of principal executive offices)	(Zip code)

Registrant’s telephone number, including area code      44 1256 894 000

(Former name or former address, if changed since last report)

Item 7. Financial Statements and Exhibits

     (c) Exhibits.    The following exhibit is filed herewith:

99.1        Press Release of Shire Pharmaceuticals Group plc dated March 11, 2004, reporting Shire's financial results for the fourth quarter of 2003 and the year ended December 31, 2003.

Item 12. Results of Operations and Financial Condition

     On March 11, 2004, Shire Pharmaceuticals Group plc issued a press release announcing its financial results for the fourth quarter of 2003 and the year ended December 31, 2003. A copy of the press release is furnished as Exhibit 99.1 to this report and is incorporated herein by reference.

SIGNATURE

     Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

SHIRE PHARMACEUTICALS GROUP PLC

By:    /s/ A C Russell                  
       Name: Angus Russell
       Title:   Group Finance Director

Dated: March 11, 2004

EXHIBIT INDEX

Number	Description
99.1	Press Release of Shire Pharmaceuticals Group plc dated March 11, 2004, reporting Shire’s financial results for the fourth quarter of 2003 and the year ended December 31, 2003.