<SEC-DOCUMENT>0000215457-16-005869-index.html : 20160210
<SEC-HEADER>0000215457-16-005869.hdr.sgml : 20160210
<ACCEPTANCE-DATETIME>20160210105130
ACCESSION NUMBER:		0000215457-16-005869
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20160210
DATE AS OF CHANGE:		20160210

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shire plc
		CENTRAL INDEX KEY:			0000936402
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-55755
		FILM NUMBER:		161403523

	BUSINESS ADDRESS:	
		STREET 1:		HAMPSHIRE INTL BUSINESS PARK
		STREET 2:		CHINEHAM BASINGSTOKE
		CITY:			HAMPSHIRE ENGLAND RG
		STATE:			X0
		ZIP:			RG24 8EP
		BUSINESS PHONE:		441256894000

	MAIL ADDRESS:	
		STREET 1:		HAMPSHIRE INTL BUSINESS PARK
		STREET 2:		CHINEHAM BASINGSTOKE
		CITY:			HAMPSHIRE ENGLAND RG
		STATE:			X0
		ZIP:			RG24 8EP

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire Ltd.
		DATE OF NAME CHANGE:	20080523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire plc
		DATE OF NAME CHANGE:	20051125

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHIRE PHARMACEUTICALS GROUP PLC
		DATE OF NAME CHANGE:	19980302

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BlackRock Inc.
		CENTRAL INDEX KEY:			0001364742
		STANDARD INDUSTRIAL CLASSIFICATION:	SECURITY BROKERS, DEALERS & FLOTATION COMPANIES [6211]
		IRS NUMBER:				320174431
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0226

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		55 EAST 52ND STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10055
		BUSINESS PHONE:		212-810-5300

	MAIL ADDRESS:	
		STREET 1:		55 EAST 52ND STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10055

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BlackRock, Inc.
		DATE OF NAME CHANGE:	20060929

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	New BlackRock, Inc.
		DATE OF NAME CHANGE:	20060601
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>shire.plc.txt
<TEXT>
Document 1 - file: shire.plc.txt

</DOCUMENT>
</SEC-DOCUMENT>