Exhibit 99.1

Brooks Automation Reports Fiscal Second Quarter Ended March 31, 2012 Results

CHELMSFORD, Massachusetts, May 10, 2012 – Brooks Automation, Inc. (Nasdaq:BRKS), a leading worldwide provider of automation, vacuum and instrumentation solutions for multiple markets including semiconductor manufacturing and life sciences today reported financial results for the second quarter and six-months ended March 31, 2012.

Fiscal Second Quarter of 2012 Financial and Operational Highlights:

• Revenues were $139.3 million; Order Bookings increased 20.9% sequentially to $155.3 million;

• GAAP EPS was $0.14 and EPS excluding special charges was $0.20;

• Adjusted EBITDA was $20.6 million;

• Cash, Cash Equivalents and Marketable Securities as of March 31^st were $204.3 million, or $3.10 per diluted share with no Debt;

• Generated 40 Design-in-Wins during the first six months of fiscal 2012 with OEM Customers.

Management Comments

“We generated revenue and earnings during the quarter at the high end of our guidance range due to a number of factors including 21% sequential growth in our Product Solutions segment as we had full participation in the front end semiconductor market recovery and we improved consolidated gross margin by 110 basis points on a sequential basis,” stated Steve Schwartz, President & Chief Executive Officer of Brooks. “In addition, our Life Science Systems revenue continued to grow and achieved profitability absent purchase accounting adjustments. We are pleased with the continued progression of this business segment.”

Dr. Schwartz continued, “During the first six months of this year we made improvements in many aspects of our business and will be focusing on better overhead absorption, higher gross margins and enhanced supply chain management during the second half of fiscal 2012. With our strong cash position, no debt and increasing cash flow, we are well positioned to reinvest in our business and continue to offer our customers the next generation of product and systems solutions.”

Second Quarter of Fiscal 2012 Results

Revenues for the second quarter of fiscal 2012 were $139.3 million, compared to revenues of $120.2 million in the first quarter of fiscal 2012 and $192.7 million in the second quarter of fiscal 2011, which included $49.1 million from the Contract Manufacturing business that was sold at the end of the third quarter of fiscal 2011. Revenues for the Brooks Product Solutions segment increased 21.3% on a sequential basis compared to the first fiscal quarter of 2012 with 32.2% growth in product sales into semiconductor markets. Revenues for the Brooks Life Science Systems segment increased 14.1% sequentially with strong Automated Sample Management store revenues, while revenues for the Brooks Global Services segment decreased 3.9% on lower pump service revenues.

Order bookings for the second quarter of fiscal 2012 grew 20.9% to $155.3 million, compared to order bookings in the fiscal first quarter of $128.5 million. Bookings included strong Life Science Systems orders for fiscal 2013 delivery.

Gross profit margin was 34.7% for the second quarter of fiscal 2012, compared to gross profit margins of 33.6% for the first quarter of fiscal 2012 and 32.0% for the second quarter of fiscal 2011. The second quarter of fiscal 2012 improved 110 basis points compared to the first quarter of fiscal 2012 due to a larger contribution from the higher margins Brooks Life Science Systems segment as operational performance continues to improve. Gross margins as compared to performance in 2011 are impacted by the Life Science Systems acquisitions and the Contract Manufacturing divestiture.

Net income for the second quarter of fiscal 2012 amounted to $9.5 million, or $0.14 per diluted share, which includes Life Science Systems acquisition related adjustments of $0.5 million and a $3.0 million charge related to the write-off of in-process research & development from a technology acquisition. Adjusted net income excluding these special charges was $13.0 million or $0.20 per diluted share. This compares to first quarter fiscal 2012 net income of $3.0 million or $0.05 per diluted share and $26.6 million or $0.41 per diluted share in the second quarter of fiscal 2011.

Adjusted EBITDA (Earnings before Interest, Tax, Depreciation and Amortization) for the second quarter of fiscal 2012 was $20.6 million, which compared to $10.8 million in the first quarter of fiscal 2012 and $34.1 million in the second quarter of fiscal 2011. A reconciliation of non-GAAP measures to the most nearly comparable GAAP measure follows the consolidated statements of operations, balance sheets and statements of cash flows included in this release.

Net cash provided by operating activities for the second quarter of fiscal 2012 was $16.6 million, which drove an increase in total cash and marketable securities to $204.3 million at March 31, 2012.

Six Months ended March 31, 2012 Results

Revenues for the six months ended March 31, 2012 were $259.6 million, compared to revenues of $371.0 million for the six months ended March 31, 2011, which included $95.0 million from the Contract Manufacturing business that was sold at the end of the third quarter of fiscal 2011. Net income for the six months ended March 31, 2012, including the impact of certain adjustments and charge-offs were $12.5 million or $0.19 per diluted share compared to $50.1 million or $0.77 per diluted share for the six months ended March 31, 2011.

Quarterly Cash Dividend

The Company additionally announced that the Board of Directors had declared a dividend of $0.08 per share payable on June 29, 2012 to stockholders of record on June 8, 2012. Future dividend declarations, as well as the record and payment dates for such dividends, are subject to the final determination of the Company’s Board of Directors.

Guidance for Third Fiscal Quarter of Fiscal 2012

The Company announced revenue and earnings guidance for the third quarter of fiscal 2012. Revenues are expected to increase sequentially up to 5% and range between $140 million and $147 million. GAAP earnings are expected to range between $0.13 and $0.18 per diluted share and non-GAAP earnings, excluding special charges which will arise principally from certain restructuring activities, are expected to range between $0.15 and $0.20.

Conference Call

Brooks management will webcast its second quarter earnings conference today at 4:30 p.m. Eastern Time to discuss the fiscal second quarter business highlights. During the call, Company management will respond to questions concerning, but not limited to, the Company’s financial performance, business conditions and industry outlook. Their responses could contain information that has not been previously disclosed.

The call will be broadcast live over the Internet and, together with presentation materials referenced on the call, will be hosted at the Investor Relations section of Brooks’ website at www.brooks.com, and will be archived online on this website for convenient on-demand replay. In addition, you may call (888) 419-5570 (US only) or (617) 896-9871 to listen to the live broadcast. The passcode for this telephone access is 604 100 53.

About Brooks Automation, Inc.

Brooks is a leading worldwide provider of automation, vacuum and instrumentation solutions for multiple markets including semiconductor manufacturing, life sciences, and clean energy. Our technologies, engineering competencies and global service capabilities provide customers speed to market, and ensure high uptime and rapid response, which equate to superior value in their mission-critical controlled environments. Since 1978, we have been a leading partner to the global semiconductor manufacturing market and through product development initiatives and strategic business acquisitions; we have expanded our reach to meet the needs of customers in the life sciences industry, analytical & research markets and clean energy solutions. Brooks is headquartered in Chelmsford, MA, with direct operations in North America, Europe and Asia.

For more information, please visit www.brooks.com.

“Safe Harbor Statement” under Section 21E of the Securities Exchange Act of 1934

Some statements in this release are forward-looking statements made under Section 21E of the Securities Exchange Act of 1934. These statements are neither promises nor guarantees but involve risks and uncertainties, both known and unknown, that could cause Brooks’ financial and business results to differ materially from our expectations. They are based on the facts known to management at the time they are made. These forward-looking statements include statements regarding our revenue and operating margin expectations, our ability to develop further our business in new and adjacent markets, and our ability to achieve financial success in the future. Factors that could cause results to differ from our expectations include the following: volatility of the industries the Company serves, particularly the semiconductor industry; our possible inability to meet demand for our products due to difficulties in obtaining components and materials from our suppliers - particularly those manufacturing in Thailand - in required quantities and of required quality; the inability of customers to make payments to us when due; the timing and effectiveness of cost reduction and cost control measures; price competition; disputes concerning intellectual property; continuing uncertainties in global political and economic conditions, and other factors and other risks that we have described in our filings with the Securities and Exchange Commission, including but not limited to our Annual Report on Form 10-K, current reports on Form 8-K and our quarterly reports on Form 10-Q. As a result we can provide no assurance that our future results will not be materially different from those projected. Brooks expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any such statement to reflect any change in our expectations or any change in events, conditions or circumstances on which any such statement is based. Brooks undertakes no obligation to update the information contained in this press release.

BROOKS AUTOMATION, INC.

CONSOLIDATED BALANCE SHEETS

(unaudited)

(In thousands, except share and per share data)

	March 31, 2012			September 30, 2011
Assets
Current assets
Cash and cash equivalents	$	81,155		$	58,833
Restricted cash		817			1,293
Marketable securities		71,057			65,695
Accounts receivable, net		80,492			76,701
Inventories, net		105,065			107,654
Prepaid expenses and other current assets		10,051			10,348
Total current assets		348,637			320,524
Property, plant and equipment, net		66,676			68,596
Long-term marketable securities		52,059			81,290
Goodwill		88,440			84,727
Intangible assets, net		43,881			44,314
Equity investment in joint ventures		33,924			34,612
Other assets		3,059			2,557
Total assets	$	636,676		$	636,620
Liabilities and equity
Current liabilities
Accounts payable	$	46,048		$	40,199
Deferred revenue		10,595			14,073
Accrued warranty and retrofit costs		7,281			7,438
Accrued compensation and benefits		12,820			17,288
Accrued restructuring costs		120			293
Accrued income taxes payable		3,273			4,015
Accrued expenses and other current liabilities		13,329			12,433
Total current liabilities		93,466			95,739
Income taxes payable		10,318			11,728
Long-term pension liability		7,209			7,161
Other long-term liabilities		3,401			3,394
Total liabilities		114,394			118,022
Contingencies
Equity
Preferred stock, $0.01 par value, 1,000,000 shares authorized, no shares issued and outstanding		—			—
Common stock, $0.01 par value, 125,000,000 shares authorized, 79,778,340 shares issued and 66,316,471 shares outstanding at March 31, 2012, 79,737,189 shares issued and 66,275,320 shares outstanding at September 30, 2011		798			797
Additional paid-in capital		1,813,848			1,809,287
Accumulated other comprehensive income		16,710			19,480
Treasury stock at cost, 13,461,869 shares at March 31, 2012 and September 30, 2011		(200,956	)		(200,956	)
Accumulated deficit		(1,108,720	)		(1,110,599	)
Total Brooks Automation, Inc. stockholders’ equity		521,680			518,009
Noncontrolling interest in subsidiaries		602			589
Total equity		522,282			518,598
Total liabilities and equity	$	636,676		$	636,620

BROOKS AUTOMATION, INC.

CONSOLIDATED STATEMENTS OF OPERATIONS

(unaudited)

(In thousands, except per share data)

	Three months ended March 31,						Six months ended March 31,
	2012			2011			2012			2011
Revenues
Product	$	117,621		$	174,936		$	214,719		$	336,125
Services		21,716			17,715			44,846			34,893
Total revenues		139,337			192,651			259,565			371,018
Cost of revenues
Product		75,443			118,661			139,732			227,634
Services		15,612			12,316			31,194			24,391
Total cost of revenues		91,055			130,977			170,926			252,025
Gross profit		48,282			61,674			88,639			118,993
Operating expenses
Research and development		12,529			9,442			24,478			18,340
Selling, general and administrative		24,270			25,245			51,012			49,723
Restructuring charges		42			246			245			460
In-process research and development		3,026			—			3,026			—
Total operating expenses		39,867			34,933			78,761			68,523
Operating income		8,415			26,741			9,878			50,470
Interest income		273			261			552			536
Interest expense		—			(28	)		(7	)		(29	)
Other income (expense), net		(51	)		256			295			417
Income before income taxes and equity in earnings of joint ventures		8,637			27,230			10,718			51,394
Income tax provision (benefit)		(659	)		1,035			(359	)		2,023
Income before equity in earnings of joint ventures		9,296			26,195			11,077			49,371
Equity in earnings of joint ventures		195			408			1,420			718
Net income	$	9,491		$	26,603		$	12,497		$	50,089
Net income attributable to noncontrolling interests		(5	)		(18	)		(13	)		(18	)
Net income attributable to Brooks Automation, Inc.	$	9,486		$	26,585		$	12,484		$	50,071
Basic net income per share attributable to Brooks Automation, Inc. common stockholders	$	0.15		$	0.41		$	0.19		$	0.78
Diluted net income per share attributable to Brooks Automation, Inc. common stockholders	$	0.14		$	0.41		$	0.19		$	0.77
Shares used in computing earnings per share
Basic		65,038			64,516			64,925			64,388
Diluted		65,828			65,061			65,552			64,801

BROOKS AUTOMATION, INC.

CONSOLIDATED STATEMENTS OF CASH FLOWS

(unaudited)

(In thousands)

	Six months ended March 31,
	2012			2011
Cash flows from operating activities
Net income	$	12,497		$	50,089
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation and amortization		10,621			8,312
Stock-based compensation		4,924			3,616
Amortization of premium on marketable securities		1,244			921
Undistributed earnings of joint ventures		(1,420	)		(718	)
(Gain) loss on disposal of long-lived assets		(47	)		14
Changes in operating assets and liabilities, net of acquisitions and disposals:
Accounts receivable		(2,951	)		(6,199	)
Inventories		3,540			(9,744	)
Prepaid expenses and other current assets		(732	)		2,853
Accounts payable		5,894			(4,807	)
Deferred revenue		(3,949	)		92
Accrued warranty and retrofit costs		(172	)		(538	)
Accrued compensation and benefits		(5,630	)		(2,443	)
Accrued restructuring costs		(168	)		(1,956	)
Accrued expenses and other current liabilities		(1,954	)		(574	)
Net cash provided by operating activities		21,697			38,918
Cash flows from investing activities
Purchases of property, plant and equipment		(4,384	)		(3,175	)
Purchases of marketable securities		(39,097	)		(71,225	)
Sale/maturity of marketable securities		61,970			37,551
Acquisition, net of cash acquired		(8,716	)		—
Decrease (increase) in restricted cash		476			(3,788	)
Net cash provided by (used in) investing activities		10,249			(40,637	)
Cash flows from financing activities
Proceeds from the issuance of common stock, net of issuance costs		842			681
Common stock dividend paid		(10,442	)		—
Net cash (used in) provided by financing activities		(9,600	)		681
Effects of exchange rate changes on cash and cash equivalents		(24	)		543
Net increase (decrease) in cash and cash equivalents		22,322			(495	)
Cash and cash equivalents, beginning of period		58,833			59,823
Cash and cash equivalents, end of period	$	81,155		$	59,328

Notes on Non-GAAP Financial Measures:

The information in this press release is for: internal managerial purposes; when publicly providing guidance on future results; and as a means to evaluate period-to-period comparisons. These financial measures are used in addition to and in conjunction with results presented in accordance with GAAP and should not be relied upon to the exclusion of GAAP financial measures. Management believes these financial measures provide an additional way of viewing aspects of our operations, that, when viewed with our GAAP results and the accompanying reconciliations to the corresponding GAAP financial measures, provide a more complete understanding of our business. Management strongly encourages investors to review our financial statements and publicly-filed reports in their entirety and not rely on any single measure.

The press release includes financial measures which exclude the effects of non-recurring income and special charges such as restructuring charges and acquisition related charges. Management believes these measures are useful to investors because it eliminates accounting charges that do not reflect Brooks' day-to-day operations. A table reconciling income and diluted earnings per share from operations is presented below:

	Quarter ended
	March 31, 2012				December 31, 2011				March 31, 2011
	$		per share		$		per share		$		per share
Net income attributable to Brooks Automation, Inc.	$	9,486	$	0.14	$	2,998	$	0.05	$	26,585	$	0.41
Purchase accounting impact on contracts acquired		471		0.01		360		0.01		—		—
Restructuring charges		42		0.00		203		0.00		246		0.00
Merger costs		—		—		221		0.00		—		—
In-process R&D purchased		3,026		0.05		—		—		—		—
Adjusted net income attributable to Brooks Automation, Inc.		13,025		0.20		3,782		0.06		26,831		0.41
Stock-based compensation		3,181		0.05		1,743		0.03		2,407		0.04
Adjusted net income attributable to Brooks Automation, Inc., excluding stock-based compensation	$	16,206	$	0.25	$	5,525	$	0.08	$	29,238	$	0.45

	Six Months Ended
	March 31, 2012				March 31, 2011
	$		per share		$		per share
Net income attributable to Brooks Automation, Inc.	$	12,484	$	0.19	$	50,071	$	0.77
Purchase accounting impact on contracts acquired		831		0.01		—		—
Restructuring charges		245		0.00		460		0.01
Merger costs		221		0.00		—		—
In-process R&D purchased		3,026		0.05		—		—
Adjusted net income attributable to Brooks Automation, Inc.	$	16,807		0.26	$	50,531		0.78
Stock-based compensation		4,924		0.08		3,616		0.06
Adjusted net income attributable to Brooks Automation, Inc. - excluding stock-based compensation	$	21,731	$	0.33	$	54,147	$	0.84

	Quarter ended									Six months ended
	Mar 31, 2012			Dec 31, 2011			Mar 31, 2011			Mar 31, 2012			Mar 31, 2011
Net income attributable to Brooks Automation, Inc.	$	9,486		$	2,998		$	26,585			12,484			50,071
Less: Interest income		(273	)		(279	)		(261	)		(552	)		(536	)
Add: Interest expense		—			7			28			7			29
Add: Income tax provision (benefit)		(659	)		300			1,035			(359	)		2,023
Add: Depreciation		3,280			3,262			3,109			6,542			6,454
Add: Amortization of completed technology		935			789			480			1,724			959
Add: Amortization of acquired intangible assets		1,138			1,217			449			2,355			899
Add: Stock-based compensation		3,181			1,743			2,407			4,924			3,616
Add: Restructuring charges		42			203			246			245			460
Add: Purchase accounting impact on contracts acquired		471			360			—			831			—
Add: Merger costs		—			221			—			221			—
Add: In-process R&D purchased		3,026			—			—			3,026			—
Adjusted EBITDA	$	20,627		$	10,821		$	34,078		$	31,448		$	63,975

Contact:

Brooks Automation, Inc.

Barbara Culhane

Corporate Marketing Manager

978-262-2400

barbara.culhane@brooks.com

John Mills

Senior Managing Director

ICR, LLC

310-954-1105

john.mills@icrinc.com