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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate to Effective Tax Rate (Detail)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]      
Federal statutory rate 21.00% 21.00% 21.00%
State income taxes, net of federal benefit 0.40% 2.30% 1.90%
Domestic manufacturing deduction (2.60%) (2.10%) (1.40%)
Research and development tax credit (12.60%) (4.00%) (3.10%)
Stock based compensation (0.30%) 0.20% (1.40%)
Valuation allowance 1.70% 0.50% 0.20%
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent 5.60% 1.70% 1.30%
Other permanent differences (1.60%) 1.00% 3.40%
Effective income tax rate for continuing operations 11.60% 20.60% 21.90%