0001181431-12-054549.txt : 20121012 0001181431-12-054549.hdr.sgml : 20121012 20121012081242 ACCESSION NUMBER: 0001181431-12-054549 CONFORMED SUBMISSION TYPE: 3 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20121010 FILED AS OF DATE: 20121012 DATE AS OF CHANGE: 20121012 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Regulus Therapeutics Inc. CENTRAL INDEX KEY: 0001505512 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 264738379 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 3545 JOHN HOPKINS COURT STREET 2: SUITE 210 CITY: SAN DIEGO STATE: CA ZIP: 92121 BUSINESS PHONE: 858-202-6300 MAIL ADDRESS: STREET 1: 3545 JOHN HOPKINS COURT STREET 2: SUITE 210 CITY: SAN DIEGO STATE: CA ZIP: 92121 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: ASTRAZENECA PLC CENTRAL INDEX KEY: 0000901832 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 3 SEC ACT: 1934 Act SEC FILE NUMBER: 001-35670 FILM NUMBER: 121141052 BUSINESS ADDRESS: STREET 1: 2 KINGDOM STREET - LEGAL DEPARTMENT CITY: LONDON STATE: X0 ZIP: W2 6BD BUSINESS PHONE: 011 44 20 7304 5000 MAIL ADDRESS: STREET 1: 2 KINGDOM STREET - LEGAL DEPARTMENT CITY: LONDON STATE: X0 ZIP: W2 6BD FORMER NAME: FORMER CONFORMED NAME: ZENECA GROUP PLC DATE OF NAME CHANGE: 19930422 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: ASTRAZENECA AB CENTRAL INDEX KEY: 0000928966 STATE OF INCORPORATION: NY FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 3 SEC ACT: 1934 Act SEC FILE NUMBER: 001-35670 FILM NUMBER: 121141051 BUSINESS ADDRESS: STREET 1: V?STRA M?LAREHAMNEN 9 CITY: S?DERT?LJE STATE: V7 ZIP: SE-151 85 BUSINESS PHONE: 0044 (0) 20 7604 800 MAIL ADDRESS: STREET 1: V?STRA M?LAREHAMNEN 9 CITY: S?DERT?LJE STATE: V7 ZIP: SE-151 85 FORMER NAME: FORMER CONFORMED NAME: ASTRA AB DATE OF NAME CHANGE: 19981116 FORMER NAME: FORMER CONFORMED NAME: ASTRA AKTIEBOLAG DATE OF NAME CHANGE: 19960718 3 1 rrd358170.xml FORM 3 X0206 3 2012-10-10 0 0001505512 Regulus Therapeutics Inc. RGLS 0000901832 ASTRAZENECA PLC 2 KINGDOM STREET LONDON X0 W2 6BD UNITED KINGDOM 0 0 1 0 0000928966 ASTRAZENECA AB 85 SODERTALJE V7 SE-151 SWEDEN 0 0 1 0 COMMON STOCK 6250000 I See footnote The securities are owned directly by AstraZeneca AB, a wholly-owned, indirect subsidiary of AstraZeneca PLC. AstraZeneca is an indirect beneficial owner of the reported securities. Exhibit 24 - Power of Attorney /s/ A C N Kemp, Authorized Signatory 2012-10-12 EX-24. 2 rrd321428_363368.htm POWER OF ATTORNEY rrd321428_363368.html 
                                   Exhibit 24

                               POWER OF ATTORNEY

The undersigned hereby makes, constitutes and appoints AstraZeneca PLC as its
true and lawful attorney-in-fact and agent, with full power of substitution and
re-substitution for it and in its name, place and stead, in any and all
capacities, to execute and deliver any Schedule 13G, Schedule 13D, Forms 3, 4 or
5, or any amendments, restatements, supplements, and/or exhibits thereto,
required to be filed with the U.S. Securities and Exchange Commission under the
Securities Exchange Act of 1934, as amended, on behalf of the undersigned with
regard to any securities owned by the undersigned; and, in connection with the
foregoing, to execute and deliver all documents, acknowledgements, consents and
other agreements and to take such further action as may be necessary or
convenient in order to more effectively carry out the intent and purpose of the
foregoing.

Dated: October 12, 2012

                                        ASTRAZENECA AB

                                        By:   /s/ Jan-Olof Jacke
                                           -------------------------------------
                                        Name: Jan-Olof Jacke
                                        Title: Authorized Signatory