The key inputs into the Black-Scholes Option Pricing Model used to estimate the fair value of the Pre-Funded Warrants as of the issuance on June 21, 2022 were as follows:


Risk-free interest rate			3.21%
Expected volatility			90.0%
Term until liquidation (years)			2.00
Stock price (pre-Reverse Stock Split)			$1.11
Strike price (exercise fee)			$4.5 million

The following table sets forth significant assumptions used in the Monte Carlo model for performance-based options to determine the fair value of the options awarded in June 2023 at the date of grant for the year ended December 31, 2023.


	June 7, 2023 Awards
Risk-free interest rate	3.79	%
Expected volatility of common stock	110.00	%
Expected life of options in years	10.0
Dividend yield	—	%

The following table sets forth significant assumptions used in the Black-Scholes model for market-based options to determine the fair value of the options awarded in December 2023 at the date of grant for the year ended December 31, 2023.


	December 5, 2023 Awards
Risk-free interest rate	4.13	%
Expected volatility of common stock	90.60	%
Expected life of options in years	6.5
Dividend yield	—	%

The key inputs to the Black-Scholes Model used to estimate the fair value of the vested equity awards, as of the date of the termination were as follows:


	January 19, 2023
Risk-free interest rate	3.79		%
Expected volatility of common stock	90.00		%
Expected life of options in years	6.92
Stock price (pre-Reverse Stock Split basis)	$	1.37
Strike Price	$	1.93