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Note 9 - Net Loss Per Share (Tables)
3 Months Ended
Mar. 31, 2023
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   

March 31,

 
   

2023

   

2022

 
                 

Stock options to purchase common stock

    2,168,450       1,616,364  

Unvested restricted stock units

    2,734       5,468  

Common stock warrants

    2,424,724       2,424,724  

Total

    4,595,908       4,046,556