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Note 9 - Net Loss Per Share (Tables)
9 Months Ended
Sep. 30, 2022
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   

September 30,

 
   

2022

   

2021

 
                 

Stock options to purchase common stock

    2,148,732       1,684,066  

Unvested restricted stock units

    2,734       5,468  

Common stock warrants

    2,424,724       2,424,724  

Total

    4,576,190       4,114,258