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Note 9 - Net Loss Per Share (Tables)
6 Months Ended
Jun. 30, 2022
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
  

June 30,

 
  

2022

  

2021

 
         

Stock options to purchase common stock

  2,060,836   1,685,059 

Unvested restricted stock units

  2,734   5,468 

Common stock warrants

  2,424,724   2,424,724 

Total

  4,488,294   4,115,251