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Note 5 - Property and Equipment, Net (Tables)
12 Months Ended
Dec. 31, 2020
Notes Tables  
Property, Plant and Equipment [Table Text Block]
   
December 31,
 
   
2020
   
2019
 
Computer equipment and software
  $
159
    $
132
 
Laboratory and manufacturing equipment
   
550
     
550
 
Furniture and fixtures
   
59
     
55
 
Leasehold improvements
   
332
     
332
 
Construction in progress
   
70
     
69
 
Property and equipment, gross
   
1,170
     
1,138
 
Less accumulated depreciation
   
(1,025
)    
(957
)
Property and equipment, net
  $
145
    $
181