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Represents the length of time of each of the automatic renewal periods for the term of a consulting agreement.

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The cash inflow from the additional capital contribution to the entity from issuance of common stock and warrants.

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No definition available.

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Represents the percentage of the entity that is owned by a specified related party.

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The amount of share-based payment arrangement expense classified as options modifications.

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Number of securities into which each warrant or right may be converted. For example, but not limited to, each warrant may be converted into two shares.

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No definition available.

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Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

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The cash outflow for cost incurred directly with the issuance of an equity security.

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The cash inflow from the issuance of a long-term debt instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder.

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Per share amount received by subsidiary or equity investee for each share of common stock issued or sold in the stock transaction.

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No definition available.

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Amount of noncash expense for share-based payment arrangement.

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Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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Gross number of share options (or share units) granted during the period.

+ References

No definition available.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Number of new stock issued during the period.

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Note 16 - Related Party Transactions (Details Textual) - USD ($)				1 Months Ended	12 Months Ended
	Nov. 26, 2019	Jul. 05, 2019	Dec. 24, 2018	Aug. 31, 2016	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017	Aug. 19, 2016
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)	515,036				254,785
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)					$ 18.99	$ 25.20
Share-based Payment Arrangement, Noncash Expense, Total					$ 2,722,000	$ 2,774,000	$ 2,707,000
Stock Issued During Period, Shares, New Issues (in shares)			592,592
Sale of Stock, Price Per Share (in dollars per share)			$ 6.75
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right (in shares)			0.5
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)			296,296
Proceeds from Issuance of Common Stock and Warrants			$ 3,800,000		10,452,000	4,000,000
Payments of Stock Issuance Costs			$ 200,000		1,259,000	200,000
Convertible Promissory Note [Member]
Proceeds from Convertible Debt		$ 625,000
Chairman and Chief Executive Officer of OPKO [Member]
Related Party, Ownership Percentage								5.00%
OPKO [Member] \| Consulting Services [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)				46,553
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period (Year)				4 years
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)				$ 16.20
Consulting Agreement, Term (Year)				4 years
Consulting Agreement, Term, Length of Automatic Renewal Periods (Year)				1 year
OPKO [Member] \| Chairman and Chief Executive Officer of OPKO [Member]
Share-based Payment Arrangement, Noncash Expense, Total					225,000	$ 142,000	$ 480,000
Share-based Payment Arrangement, Options Modifications					$ 167,000