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Note 10 - Share-based Compensation (Details Textual) - USD ($)
12 Months Ended
Nov. 26, 2019
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Share Price (in dollars per share)   $ 3.68    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value   $ 0 $ 3,000 $ 400,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value (in dollars per share)   $ 3.87 $ 15.48 $ 52.20
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares) 515,036 254,785    
Share-based Payment Arrangement, Noncash Expense, Total   $ 2,722,000 $ 2,774,000 $ 2,707,000
Employees [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)   254,785 188,716  
Non-employee Directors and Employees [Member]        
Share-based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount   $ 3,400,000    
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)   2 years 36 days    
Consultants [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)     0 5,139
Non-employees [Member]        
Share-based Payment Arrangement, Noncash Expense, Total     $ 176,000 $ 768,000
The 2016 Plan [Member]        
Annual Increase, Number of Common Shares (in shares)   268,997    
Annual Increase, Percentage of Common Shares Outstanding   4.00%    
Share-based Payment Arrangement, Option [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period (Year)   4 years    
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)   10 years    
Share-based Payment Arrangement, Option [Member] | The 2016 Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)   461,605    
Restricted Stock Units (RSUs) [Member]        
Share-based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount   $ 171,000    
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)   36 days    
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)   34,713    
Restricted Stock Units (RSUs) [Member] | Non-employee Directors and Employees [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)   34,713