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Note 14 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2018
Notes Tables  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
   
Years ended December 31,
 
   
2018
   
2017
   
2016
 
Tax at federal statutory rate
  $
(2,937
)   $
(4,185
)   $
(3,505
)
State, net of federal benefit
   
(455
)    
(1,238
)    
(315
)
Research and development credit
   
(236
)    
(135
)    
(89
)
Stock-based compensation
   
440
     
344
     
136
 
Nondeductible interest
   
     
     
590
 
Warrant and derivative revaluation
   
     
     
328
 
Change in Federal tax rate
   
     
8,172
     
 
Other
   
22
     
7
     
94
 
Change in valuation allowance
   
3,166
     
(2,965
)    
2,761
 
Total provision for income taxes
  $
    $
    $
 
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
   
December 31,
 
   
2018
   
2017
 
Accrued compensation
  $
84
    $
110
 
Inventory adjustments
   
276
     
449
 
Depreciation and amortization - noncurrent
   
113
     
146
 
Share-based compensation
   
648
     
558
 
Net operating loss and tax credit carryforwards - noncurrent
   
20,698
     
17,368
 
Other
   
12
     
34
 
Gross deferred tax asset
   
21,831
     
18,665
 
Valuation allowance
   
(21,831
)    
(18,665
)
Net deferred tax asset
  $
    $
 
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
   
December 31,
 
   
2018
   
2017
 
Balance, beginning of year
  $
725
    $
608
 
Additions based on tax positions related to the current year
   
166
     
117
 
Additions (reductions) for tax positions related to prior years
   
     
 
Balance, end of year
  $
891
    $
725