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Note 10 - Net Loss Per Share (Tables)
9 Months Ended
Sep. 30, 2019
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
September 30,
 
   
2019
   
2018
 
Stock options to purchase common stock
   
848,148
     
616,567
 
Unvested restricted stock units
   
62,135
     
29,706
 
Common stock warrants
   
2,435,808
     
-
 
Total
   
3,346,091
     
646,273