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Note 5 - Property and Equipment, Net
3 Months Ended
Mar. 31, 2019
Notes to Financial Statements  
Property, Plant and Equipment Disclosure [Text Block]
(
5
)      Property and Equipment, Net
 
Property and equipment, net consisted of the following (in thousands):
 
   
March 31,
   
December 31,
 
   
2019
   
2018
 
Computer equipment and software
  $
121
     
119
 
Laboratory and manufacturing equipment
   
532
     
481
 
Furniture and fixtures
   
55
     
55
 
Leasehold improvements
   
332
     
332
 
Construction in progress
   
3
     
3
 
Property and equipment, gross
   
1,043
     
990
 
Less accumulated depreciation
   
(868
)    
(845
)
Property and equipment, net
  $
175
     
145
 
 
 
Depreciation expense totaled approximately
$23,000
and
$22,000
for the
three
months ended
March 31, 2019
and
2018,
respectively.