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Note 6 - Property and Equipment, Net
12 Months Ended
Dec. 31, 2018
Notes to Financial Statements  
Property, Plant and Equipment Disclosure [Text Block]
(
6
)
Property and Equipment, Net
 
Property and equipment, net consist of the following (in thousands):
 
   
December 31,
 
   
2018
   
2017
 
Computer equipment and software
  $
119
     
106
 
Laboratory and manufacturing equipment
   
481
     
447
 
Furniture and fixtures
   
55
     
48
 
Leasehold improvements
   
332
     
326
 
Construction in progress
   
3
     
 
Property and equipment, gross
   
990
     
927
 
Less accumulated depreciation
   
(845
)    
(758
)
Property and equipment, net
  $
145
     
169
 
 
Depreciation expense totaled approximately
$88,000,
$78,000
and
$39,000
for the years ended
December 31, 2018,
2017
and
2016,
respectively. All of the Company’s property and equipment is located in the United States.