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Note 10 - Net Loss Per Share (Tables)
6 Months Ended
Jun. 30, 2017
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
 
 
June 30,
 
 
 
2017
 
 
2016
 
Stock options to purchase common stock
   
48,103,603
     
12,464,656
 
Restricted stock units
   
1,176,000
     
-
 
Total
   
49,279,603
     
12,464,656