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Note 8 - Share-based Compensation - Nonemployee Stock Option Valuation Assumptions (Details) - Non-employee Stock Options [Member]
3 Months Ended
Mar. 31, 2017
Risk-free interest rate, minimum 2.37%
Risk-free interest rate, maximum 2.40%
Volatility 89.00%
Dividend yield 0.00%
Minimum [Member]  
Expected terms (Year) 9 years 146 days
Maximum [Member]  
Expected terms (Year) 9 years 292 days