Document Format Files
| Seq | Description | Document | Type | Size |
|---|---|---|---|---|
| 1 | FORM S-1 | S-1 | 366331 | |
| 2 | FORM OF UNDERWRITING AGREEMENT | EX-1.1 | 101680 | |
| 3 | CERTIFICATE OF INCORPORATION OF THE COMPANY | EX-3.1 | 3877 | |
| 4 | FORM OF RESTATED CERTIFICATE OF INCORPORATION | EX-3.2 | 10523 | |
| 5 | BYLAWS OF THE COMPANY | EX-3.3 | 69934 | |
| 6 | OPINION OF WILSON SONSINI GOODRICH & ROSATI | EX-5.1 | 2672 | |
| 7 | 1997 EMPLOYEE STOCK PURCHASE PLAN | EX-10.1 | 33556 | |
| 8 | 1995 STOCK PLAN AND FORM OF STOCK OPTION AGREEMENT | EX-10.2 | 86638 | |
| 9 | SERIES A PREFERRED STOCK PURCHASE AGREEMENT | EX-10.3 | 257181 | |
| 10 | NOTE AND WARRANT PURCHASE AGREEMENT | EX-10.4 | 52915 | |
| 11 | SERIES B PREFERRED STOCK PURCHASE AGREEMENT | EX-10.5 | 197972 | |
| 12 | SERIES C PREFERRED STOCK PURCHASE AGREEEMENT | EX-10.6 | 180128 | |
| 13 | STOCK PURCHASE AGREEMENT (MARK A. SAMUELS) | EX-10.7 | 31290 | |
| 14 | STOCK PURCHASE AGREEMENT (KEITH D. IGNOTZ) | EX-10.8 | 31208 | |
| 15 | ASSIGNMENT AND BILL OF SALE | EX-10.9 | 3406 | |
| 16 | SECURITY AGREEMENT (MARK A. SAMUELS) | EX-10.10 | 14888 | |
| 17 | SECURITY AGREEMENT (KEITH D. IGNOTZ) | EX-10.11 | 14962 | |
| 18 | LICENSE AGREEMENT BETWEEN GTRC AND LAO | EX-10.12(A) | 16551 | |
| 19 | AGREEMENT FOR PURCHASE AND SALE OF TECHNOLOGY | EX-10.12(B) | 27319 | |
| 20 | FIRST AMENDMENT TO LICENSE AGREEMENT | EX-10.12(C) | 5434 | |
| 21 | CLINICAL RESEARCH STUDY AGREEMENT | EX-10.13 | 18682 | |
| 22 | DEVELOPMENT AND LICENSE AGREEMENT | EX-10.14(A) | 117845 | |
| 23 | SUPPLY AGREEMENT DATED JANUARY 5, 1996 | EX-10.14(B) | 48825 | |
| 24 | SPONSORED RESEARCH AGREEMENT, NO. SR95-006 | EX-10.15 | 26180 | |
| 25 | SOLE COMMERCIAL PATENT LICENSE AGREEMENT | EX-10.16 | 30087 | |
| 26 | JOINT DEVELOPMENT AGREEMENT DATED JULY 10, 1995 | EX-10.17 | 29190 | |
| 27 | LICENSE AGREEMENT DATED NOVEMBER 22, 1995 | EX-10.18(A) | 39083 | |
| 28 | AMENDMENT OF LICENSE AGREEMENT | EX-10.18(B) | 2147 | |
| 29 | LICENSE AND JOINT DEVELOPMENT AGREEMENT | EX-10.19 | 127645 | |
| 30 | PATENT LICENSE AGREEMENT | EX-10.20 | 36814 | |
| 31 | PUCHASING AND LICENSING AGREEMENT | EX-10.21 | 159748 | |
| 32 | RESEARCH SERVICES AGREEMENT | EX-10.22 | 12548 | |
| 33 | RESEARCH AND DEVELOPMENT AND LICENSE AGREEMENT | EX-10.23 | 339222 | |
| 34 | LEASE DATED SEPTEMBER 21, 1993 | EX-10.24 | 117534 | |
| 35 | CALCULATION OF EARNINGS PER SHARE | EX-11.1 | 1875 | |
| 36 | LIST OF SUBSIDIARIES OF THE COMPANY | EX-21.1 | 265 | |
| 37 | CONSENT OF ARTHUR ANDERSEN LLP | EX-23.1 | 394 | |
| 38 | CONSENT OF FLESHNER & KIM | EX-23.3 | 425 | |
| 39 | CONSENT OF KILPATRICK & STOCKTON | EX-23.4 | 418 | |
| 40 | CONSENT OF THORPE, NORTH & WESTERN | EX-23.5 | 437 | |
| 41 | CONSENT OF MEDICAL DEVICE CONSULTANTS | EX-23.6 | 464 | |
| 42 | FINANCIAL DATA SCHEDULE | EX-27.1 | 2295 | |
| Complete submission text file | 0000891618-97-000930.txt | 2626667 |
IRS No.: 582029543 | State of Incorp.: DE | Fiscal Year End: 1231
Type: S-1 | Act: 33 | File No.: 333-22429 | Film No.: 97544844