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Equity Incentive Plans - Summary of Options Activity (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Summary of the activity of stock option awards, shares    
Options outstanding, Beginning Balance (in Shares) 1,847  
Options granted (in shares) 340  
Options forfeited/canceled/expired (in shares) (83)  
Options outstanding, Ending Balance (in Shares) 2,104 1,847
Options vested and expected to vest (in Shares) 1,996  
Options exercisable (in Shares) 1,329  
Summary of the activity of stock option awards, weighted average exercise price    
Options outstanding, Beginning Balance, Wtd. Avg. Exercise Price (in dollars per share) $ 19.92  
Options granted, Wtd. Avg. Exercise Price (in dollars per share) 5.76  
Options forfeited/canceled/expired, Wtd. Avg. Exercise Price (in dollars per share) 17.99  
Options outstanding, Ending Balance, Wtd. Avg. Exercise Price (in dollars per share) 17.74 $ 19.92
Options vested and expected to vest, Wtd. Average Exercise Price (in dollars per share) 18.25  
Options exercisable, Wtd. Avg. Exercise Price (in dollars per share) $ 22.67  
Options outstanding, Ending Balance, Wtd. Avg. Remaining Contractual Term 6 years 7 months 24 days 6 years 2 months 23 days
Options vested and expected to vest, Wtd. Avg Remaining Contractual Term 6 years 6 months 3 days  
Options exercisable, Wtd. Avg. Remaining Contractual Term 5 years 3 months 7 days  
Options outstanding, Average Intrinsic Value $ 286 $ 73
Options vested and expected to vest at March 31, 2022 $ 238