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Equity Incentive Plans - Summary of Options Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Summary of the activity of stock option awards, shares      
Options outstanding, Beginning Balance (in Shares) 1,951,000    
Options granted (in shares) 478,000 500,000 400,000
Options exercised (in Shares) (2,000)    
Options forfeited/canceled (in shares) (580,000)    
Options outstanding, Ending Balance (in Shares) 1,847,000 1,951,000  
Options vested and expected to vest (in Shares) 1,782,000    
Options exercisable (in Shares) 1,105,000    
Summary of the activity of stock option awards, weighted average exercise price      
Options outstanding, Beginning Balance, Wtd. Avg. Exercise Price (in dollars per share) $ 22.07    
Options granted, Wtd. Avg. Exercise Price (in dollars per share) 7.52    
Options exercised, Wtd. Avg. Exercise Price (in dollars per share) 7.52    
Options forfeited/canceled, Wtd. Avg. Exercise Price (in dollars per share) 17.01    
Options outstanding, Ending Balance, Wtd. Avg. Exercise Price (in dollars per share) 19.92 $ 22.07  
Options vested and expected to vest, Wtd. Average Exercise Price (in dollars per share) 20.24    
Options exercisable, Wtd. Avg. Exercise Price (in dollars per share) $ 24.27    
Options outstanding, Ending Balance, Wtd. Avg. Remaining Contractual Term 6 years 2 months 23 days 6 years 7 months 13 days  
Options vested and expected to vest, Wtd. Avg Remaining Contractual Term 6 years 1 month 20 days    
Options exercisable, Wtd. Avg. Remaining Contractual Term 4 years 10 months 9 days    
Options outstanding, Ending Balance, Average Intrinsic Value $ 73    
Options vested and expected to vest at December 31, 2021 65    
Options exercisable at December 31, 2021 1    
Intrinsic value of options exercised     $ 433
Fair value of shares vested $ 925 $ 1,061 $ 971