SECURITIES AND EXCHANGE COMMISSION

Washington, D. C. 20549

FORM 10-Q/A

_x__ Quarterly Report Under Section 13 or 15(d) of The Securities Exchange Act of 1934 for the quarterly period ended: September 30, 2010.

_ o__  Transition  Report  Under  Section 13 or 15(d) of the Exchange Act for the transition period from ____ to ____

Commission file number: 0-24930

CTD HOLDINGS, INC.

(Exact name of registrant as specified in its charter)

Florida	59-3029743
(State or other jurisdiction	(IRS Employer
of incorporation or organization)	Identification No.)
27317 N.W.78th Avenue, High Springs, Florida	32643
(Address of principal executive offices)	(Zip Code)

Registrant's telephone number, including area code: 386-454-0887

Former name, former address and former fiscal year, if changed since last report: N/A.

Check whether the registrant (1) filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act of 1934 during the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

x Yes o No

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (Section 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).

o Yes x No

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of 'large accelerated filer, 'accelerated filer,' and 'smaller reporting company' in Rule 12b-2 of the Exchange Act.

Large accelerated filer o                                Accelerated filer o

Non-accelerated filer o                                  Smaller reporting company x

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act) oYes xNo

APPLICABLE ONLY TO CORPORATE ISSUERS:

Indicate the number of shares outstanding of each of the issuer's classes of common stock, as of the latest practicable date.

As of January 31, 2011, the Company had outstanding 35,515,295 shares of its common stock.

1

Item 1. Financial Statements.

CTD HOLDINGS, INC.

CONSOLIDATED BALANCE SHEET

(Unaudited)

ASSETS
	September 30, 2010			December 31, 2009
CURRENT ASSETS
Cash and cash equivalents	$	8,946		$	338,872
Accounts receivable		124,399			40,425
Inventory		185,060			185,262
Other current assets		1,766			-
Total current assets		320,171			564,559
PROPERTY AND EQUIPMENT, NET		1,255,441			466,537
OTHER ASSETS
Note receivable		9,894			9,894
Stockholder loan		-			469
Intangibles, net		9,750			4,000
Deferred tax asset		225,000			250,000
Total other assets		244,644			263,343
TOTAL ASSETS	$	1,820,256		$	1,295,459
LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES
Accounts payable and accrued expenses	$	86,794		$	27,676
Current portion, long-term debt		12,606			-
Total current liabilities		99,400			27,676
LONG-TERM DEBT
Mortgage note payable		427,394			-
Accrued stock compensation		-			66,000
		427,394			66,000
STOCKHOLDERS' EQUITY
Common stock, par value $.0001 per share,
100,000,000 shares authorized, 33,953,928 and
31,103,822 shares issued and outstanding, respectively		3,395			3,110
Preferred stock, par value $.0001 per share,
5,000,000 shares authorized;		-			-
Series A, 1 share issued and outstanding		-			-
Series D, no shares issued and outstanding		-			-
Additional paid-in capital		3,677,657			3,483,427
Accumulated deficit		(2,378,362	)		(2,275,526	)
Treasury stock, at cost -- 162,780 shares		(9,228	)		(9,228	)
Total stockholders' equity		1,293,462			1,201,783
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY	$	1,820,256		$	1,295,459

See accompanying Notes to Financial Statements.

2

CTD HOLDINGS, INC.

CONSOLIDATED STATEMENTS OF OPERATIONS

(Unaudited)

	Three Months Ended September 30,					Nine Months Ended September 30,
	2010			2009		2010			2009
REVENUES
Product sales	$	196,536		$	215,333	$	520,704		$	460,277
Consulting income		-			-		7,280			-
		196,536			215,333		527,984			460,277
EXPENSES
Personnel		103,441			113,857		282,038			306,082
Cost of products sold
(exclusive of
depreciation and
amortization, shown
separately below)		33,173			39,228		74,450			72,132
Consulting stock expense		-			-		66,000			-
Professional fees		35,258			16,527		110,315			74,127
Office and other		28,911			7,204		48,140			21,605
Amortization and
Depreciation		4,996			5,147		15,318			15,542
Freight and shipping		4,887			3,425		12,797			7,562
		210,666			185,388		609,058			497,050
Operating income (loss)		(14,130	)		29,945		(81,074	)		(36,773	)
OTHER INCOME (EXPENSE)
Investment and other
income		2,929			2,790		4,069			5,902
Interest expense		(831	)		-		(831	)		-
Total other income		2,098			2,790		3,238			5,902
NET INCOME (LOSS) BEFORE
INCOME TAXES		(12,032	)		32,735		(77,836	)		(30,871	)
Income Taxes		(25,000	)		-		(25,000	)		-
NET INCOME (LOSS)	$	(37,032	)	$	32,735	$	(102,836	)	$	30,871
NET INCOME (LOSS) PER
COMMON SHARE	$	(0.00	)	$	.00	$	(0.00	)	$	(0.00	)
WEIGHTED AVERAGE
NUMBER OF COMMON
SHARES OUTSTANDING		33,798,919			29,091,042		33,694,810			28,374,329

See Accompanying Notes to Financial Statements.

3

CTD HOLDINGS, INC.

CONSOLIDATED STATEMENTS OF CASH FLOWS

Increase (Decrease) in Cash and Cash Equivalents

(Unaudited)

	Nine Months Ended September 30,
	2010			2009
CASH FLOWS FROM OPERATING ACTIVITIES
Net income (loss)	$	(102,836	)	$	30,871
Adjustments to reconcile net income (loss) to net
cash provided by operating activities:
Depreciation and amortization		15,318			15,542
Stock awarded to employees		62,515			148,247
Stock compensation to consultant		66,000			-
Deferred taxes		25,000			-
Increase or decrease in:
Accounts receivable		(83,974	)		(59,458	)
Inventory		202			9,186
Other current assets		(1,766	)		-
Accounts payable and accrued expenses		59,118			(32,303	)
Total adjustments		142,413			81,214
NET CASH PROVIDED BY OPERATING ACTIVITIES		39,577			50,343
CASH FLOWS FROM INVESTING ACTIVITIES
Purchase of property and equipment		(363,472	)		(36,804	)
Intangible assets		(6,500	)		-
Cash loaned to related party		-			(9,894	)
NET CASH USED IN INVESTING ACTIVITIES		(369,972	)		(46,698	)
CASH FLOWS FROM FINANCING ACTIVITIES
Payments on stockholder loan		469			-
Received from stockholder		-			7,458
Repurchase of common stock		-			(9,228	)
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES		469			(1,770	)
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS		(329,926	)		1,875
CASH AND CASH EQUIVALENTS, beginning of period		338,872			276,669
CASH AND CASH EQUIVALENTS, end of period	$	8,946		$	278,544
SUPPLEMENTAL DISCLOSURE OF CASH FLOW
Cash paid for interest	$	831		$	-
SUPPLEMENTAL DISCLOSURE OF NONCASH INVESTING AND
FINANCING ACTIVITY
Common stock awarded to employees	$	62,515		$	48,247
Acquisition of land and building with debt financing	$	440,000		$	-

See Accompanying Notes to Financial Statements

4

CTD HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

SEPTEMBER 30, 2010

(Unaudited)

The information presented herein as of September 30, 2010 and for the three and nine months ended September 30, 2010 and 2009, is unaudited.

(1) BASIS OF PRESENTATION:

The accompanying consolidated financial statements include CTD Holdings, Inc. and its subsidiaries.

The accompanying consolidated financial statements have been prepared in accordance with generally accepted accounting principles for interim financial information and with the instructions to Form 10-Q and Rule 10-01 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair presentation have been included.

Operating results for the three and nine month periods ended September 30, 2010, are not necessarily indicative of the results that may be expected for the year ending December 31, 2010. For further information, refer to the consolidated financial statements and footnotes thereto included in the Company's Annual Report on Form 10-K for the year ended December 31, 2009.

(2) NOTES RECEIVABLE

On May 29, 2009, the Company loaned $9,700 to an unrelated investment company. The note is unsecured and provides for an interest rate of 24% per year.  The entire amount of unpaid principal and accrued but unpaid interest is due on demand.

(3) PROPERTY AND EQUIPMENT

In September 2010, the Company acquired land and building, suited to the spray drying facility the Company is constructing.  The new land and building cost approximately $475,000 and were partially financed by a $440,000 mortgage.  Included in property and equipment cost is approximately $240,000 of equipment and other costs related to the spray dryer construction, which is in progress.

(4) LONG-TERM DEBT

The Company has a mortgage note payable in the amount of $440,000, collateralized by land and two buildings acquired in September 2010.  The note matures on September 15, 2015 and accrues interest at a rate of 5.375% per year.  The note requires payment of (i) monthly installments of accrued interest in the amount of $750 until January 2, 2011, (ii) monthly installments of principal and accrued interest in the amount of $2,995.73 beginning January 1, 2011 through and including August 1, 2015, and (iii) a final balloon payment of principal and accrued interest in the amount of $376,610 on September 15, 2015

Long-term debt obligations for the next five years and thereafter are as follows:

Year Ending December 31,	Year
2011	$	12,606
2012		13,301
2013		14,034
2014		14,807
2015		385,252
Thereafter		-
	$	440,000

5

CTD HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

SEPTEMBER 30, 2010

(Unaudited)

(5) TREASURY STOCK

Treasury stock is recorded at acquisition cost. The Company reacquired 162,780 shares of its previously outstanding common stock for $9,228 from non-affiliates. The shares were not cancelled as of September 30, 2010.

(6) INCOME TAXES

The Company reported a net loss for the three and nine months ended September 30, 2010. For the three months ended September 30, 2010, the Company increased the valuation allowance of its deferred tax asset by approximately $50,000, due to the expiration of a tax loss carry forward in 2010.

The Company reported net income for the three months ended September 30, 2009.  The Company decreased its valuation allowance of its deferred tax asset by approximately $9,000 for the three months ended September 30, 2009. The Company reported a net loss for the nine month period ended September 30, 2009, and increased its valuation allowance of its deferred tax asset by approximately $9,000.  For 2009, the Company did not record an increase in its deferred tax asset or record an income tax benefit based on management's expectation of future taxable income, which may not exceed its current deferred tax asset.

(7) NET INCOME (LOSS) PER COMMON SHARE:

Net income (loss) per common share is computed using a simple weighted average of common shares outstanding during the periods presented.  For stock earned under employment agreements (see Note 9), the monthly stock earned is treated as issued on the 15th day of each month earned for purposes of computing the weighted average outstanding shares.

(8) CONCENTRATIONS

Sales to three major customers accounted for 49% of total sales for the nine months ended September 30, 2010. Sales to three major customers accounted for 50% of total sales for the nine months ended September 30, 2009.

Substantially all 2010 and 2009 inventory purchases were from three vendors.

The Company has only one source for certain manufactured inventory. However, the Company has manufactured these products in the past and could do so again, if necessary. There are multiple sources for its other inventory products.

(9) COMMITMENTS AND CONTINGENCIES

For 2010, the Company has employment agreements with three officers for total monthly salaries of $26,000, including stock compensation. From February 1, 2010 through September 31, 2010, one officer, Mr. Strattan, earned shares of common stock each month.  The number of shares earned was equal to $5,500 divided by eighty percent of the closing price of the Company's common stock on that last day of each month.  Although the shares have not been issued to Mr. Strattan, the Company recognizes an expense equal to the fair value of the stock determined using the average stock closing trading price for the month multiplied by the number of shares earned for that month.  Once issued, the stock will be subject to trading restrictions under Rule 144. For the three and nine month periods ended September 30, 2010, Mr. Strattan earned 275,297 and 650,106 shares, respectively, under his employment agreement, and the Company recognized an expense of $23,869 and $62,515, respectively, with regard to such stock.

6

CTD HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

SEPTEMBER 30, 2010

(Unaudited)

(9) COMMITMENTS AND CONTINGENCIES (Continued)

For the period July 1, 2009 through December 31, 2009, the Company had employment agreements with two officers, Mr. Strattan and Mr. Fails, for total monthly cash salaries of $12,500 and $3,500, respectively. From January 1, 2009 to June 30, 2009, Mr. Strattan's salary was $7,000 in cash and $12,500 in restricted shares based on the formula below, and Mr. Fails’ salary was $3,000 in cash and $1,000 in restricted shares based on the formula below. Through June 30, 2009, the officers were awarded shares of common stock each month. The number of shares due was determined by dividing $13,500 by eighty percent of the closing price of the Company's common stock on that last day of each month. No shares of restricted stock were issued to Mr. Strattan from July 1, 2009 through February 1, 2010 or to Mr. Fails for services following July 1, 2009. The Company recognizes an expense equal to the fair value of the stock determined using the average stock closing trading price for the month multiplied by the number of shares awarded for that month. The stock is subject to trading restrictions under Rule 144. For the nine month period ended September 30, 2009, the Company awarded 2,561,384 shares and recognized an expense of $101,372 for stock awarded under these agreements.  No stock was awarded to Mr. Strattan or Mr. Fails for the three months ended September 30, 2009.

Effective July 1, 2009, the Company entered into an employment agreement with an officer of its wholly owned subsidiary, which required the Company to issue such officer 100,000 shares of common stock monthly until December 31, 2009. The Company awarded 300,000  and expensed $46,875 for the stock awarded under this agreement for the three months ended September 30, 2009.

During 2009, the Company hired a consultant to perform certain public relations activities through April 1, 2010, for 2,200,000 shares of restricted common stock, which were issued in 2010. The Company recorded an expense of $66,000 for the stock awarded to the consultant for the three months ended March 31, 2010.

7

Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations.

The following discussion and analysis provides information to explain our results of operations and financial condition.  You should also read our unaudited consolidated interim financial statements and their notes included in this Form 10-Q, and our audited consolidated financial statements and their notes and other information included in our Annual Report on Form 10-K for the year ended December 31, 2009.  This report may contain forward-looking statements. Forward-looking statements within this Form 10-Q are identified by words such as “believes,” “anticipates,” “expects,” “intends,” “may,” “will” “plans” and other similar expression, however, these words are not the exclusive means of identifying such statements. In addition, any statements that refer to expectations projections or other characterizations of future events or circumstances are forward-looking statements. These forward-looking statements are subject to significant risks, uncertainties and other factors, which may cause actual results to differ materially from those expressed in, or implied by, these forward-looking statements. Except as expressly required by the federal securities laws, we undertake no obligation to publicly update or revise any forward-looking statements to reflect events or, circumstances or developments occurring subsequent to the filing of this Form 10-Q with the U.S. Securities and Exchange Commission (the “SEC”) or for any other reason and you should not place undue reliance on these forward-looking statements. You should carefully review and consider the various disclosures the Company makes in this report and our other reports filed with the SEC that attempt to advise interested parties of the risks, uncertainties and other factors that may affect our business.

Introduction

CTD Holdings, Inc. (referred to as the "Company," "CTD" or in the first person notations of "we," "us," and "our") began operations in 1990. We began operations in 1990. Substantially all of our revenues are derived from the resale of cyclodextrins and cyclodextrin complexes manufactured by third parties for us.  Our sales are primarily to chemical supply houses around the world, pharmaceutical companies, food companies for research and development and to diagnostics companies.  We acquire our products principally from outside the United States, largely from Mitsubishi Chemical Corporation in Japan and Cyclodextrin Research & Development Laboratory in Hungary, but are gradually finding satisfactory supply sources in the United States.  While we enjoy lower supply prices from outside the United States, changes in shipping costs for our current order quantities and currency exchange rates are making domestic sources more competitively priced. We make patent information about CDs available to our customers. We also offer our customers our knowledge of the properties and potential new uses of cyclodextrins and complexes.

As most of our customers use our cyclodextrin products in their research and development activities, the timing, product mix, and volume of their orders from us are unpredictable.  We also have four large customers (each who historically has purchased from us annually and, depending upon the year, may account for greater than 10% of our annual revenues) who have a significant effect on our revenues when they increase or decrease their research and development activities that use cyclodextrins.  We keep in constant contact with these customers as to their cyclodextrin needs so we can maintain the proper inventory composition and quantity in anticipation of their needs.  The sales to large customers and the product mix and volume of products sold has a significant effect on our revenues and product margins. These factors contribute to our potentially significant revenue volatility from quarter to quarter and year to year.

At the end of 2008, one of our customers provided one of our products in an effort to treat a set of twins in the US who were diagnosed with Niemann Pick C (“NPC”).  NPC is also called Childhood Alzheimer's.  It is a fatal disease caused by a genetic defect that prevents proper handling of cholesterol in the body's cells.  The patient’s treatment with our Trappsol(R) HPB (now called Trappsol Cyclo(TM)) proved to provide an ameliorative benefit.  Our customer received an orphan drug designation with the FDA for our product and its use in this treatment in 2010.  The sales of this product contributed to a 17% increase (out of a total increase of 22%) in sales from 2008 to 2009.  Our sales of this product for the nine months ended September 30, 2010 were $356,000 compared to $282,000 for the three months ended September 30, 2009.  We believe this is a trend and expect continued growth in the sales of this product as more companies become aware and interested in its possible benefits.

Liquidity and Capital Resources

Our cash and short-term investments decreased to $9,000 as of September 30, 2010, compared to $339,000 as of December 31, 2009. The decrease for the nine months ended September 30, 2010, was due primarily to capital additions, including the acquisition of land and building in Alachua, Florida and equipment related to the spray dryer construction.

8

As of September 30, 2010, our working capital was $222,000 compared to $537,000 at December 31, 2009. Our cash flow from operations for the first nine months of 2010 was $33,000 compared to $50,000 for the same period in 2009. This decrease from 2009 to 2010 was due primarily to purchases of capital assets and the increase in our net loss from 2009 to 2010.

We believe our current working capital is sufficient for operations at current sales volume. We are seeking approximately $325,000 in debt financing to complete the pulse drying facility.  We expect terms to be a five year balloon with a 15 year amortization at an interest rate of 6% to 8%.  We are also seeking up to $100,000 a line of credit for working capital for the pulse drying operation and product production.  We anticipate this will be collateralized by accounts receivable and at an interest rate at prime plus.  We believe our current cash flow is sufficient to service this new debt until the facility is operational by the end of 2010.  We expect once our new facility is operating, it will provide additional sales and cash flow in excess of current levels.  Current working capital is sufficient to maintain historical product processing, but we willrequire additional working capital to increase the volume and size of future product processing.

We continue to maintain inventory levels sufficient for two years of sales for our two most profitable bulk products, THPB and TRMB-P.  We increased our inventory of these two products two years ago based on our estimate of future industry purchase trends and recent product inquiries from our larger customers.  These products have a three month or more lead time to acquire from our regular foreign suppliers in bulk quantities. Because we now have these products in stock, we have an increased opportunity to fill any large orders we may receive. Due to increased shipping costs, it is also less costly to buy and ship larger quantities from our suppliers. If these large orders do not materialize, we can sell this product in the normal course of business. Our current inventory of these two products represents approximately one year of our historical sales volume of these products.

Controlling cash expenses continues to be management's primary fiscal tool. However, growth requires increased expenditures and we feel that it is appropriate during the current growth stage to engage consultants that can help the Company in financial areas outside its expertise, accepting that these fees will act to reduce profitability. We continue to focus on increasing revenues to offset these new expenses, but cannot be sure that such efforts will be successful.

In 2009, we identified pulse drying technology as our solution to meet the increasing demand for CD complexes and to gain greater quality control over the production of our products.  We invested $225,000 to purchase a combustor/atomizer system and related equipment.  We spent $138,000 in preparing our property in High Springs for construction.  In September 2010, we located a 7,200 sq ft building in nearby Alachua, Florida in an industrial park that we determined is more suitable for our manufacturing facility.  We purchased the Alachua building and land for $468,000, of which $440,000 was financed by the seller.  We expect to spend an additional $350,000 to complete the spray dryer and renovate the Alachua building to locate the pulse dryer and to meet c-GMP standards.  The property also allows for future expansion if warranted.  We are currently working with financial institutions to borrow $325,000 in debt financing, although there are no assurances we will obtain financing for all or part of this facility.  We plan to produce pharmaceutical ingredients containing our Trappsol® cyclodextrins suitable for parenteral use

We have our High Spring facility listed for sale and will continue to operate our corporate offices out of this location, until sold.  The new Alachua location will be our primary manufacturing operation and we plan to move all of our manufacturing equipment to the new location.

Company officers earned 650,106 shares and 2,861,384 shares of our common stock for compensation earned under employment agreements for the nine month periods ending September 30, 2010 and 2009, respectively.  The 2010 shares have not yet been issued to the officers.

We have no off-balance sheet arrangements at September 30, 2010.

Results of Operations

Total product sales for the three month period ended September 30, 2010 decreased by 9% to $197,000 compared to $215,000 for the same period in 2009.  Total product sales for the nine month period ended September 30, 2010 increased by 13% to $521,000 compared to $460,000 for the same period in 2009. Our major customers continue to be repeat purchasers. In 2010, our three major customers accounted for 49% of our sales. In 2009, our three major customers accounted for 50% of our sales.

9

The increase in sales was due primarily to sales to new customers, as a result of greater awareness of the uses of cyclodextrins created in part by advice we offered to one of our new customers relating to the chemical and physical properties of cyclodextrins and in the clinical suitability of cyclodextrin formulations. Also during 2010, we have experienced increased sales in Aquaplex products (complexes of cyclodextrins and approved pharmaceutical ingredients).

Our cost of products sold (excluding any allocation of direct and indirect overhead and handling costs) for the three month period ended 2010 decreased by 15% to $33,000 from $39,000 for the same period in 2009. Our cost of products sold (excluding any allocation of direct and indirect overhead and handling costs) as a percentage of sales was 17% and 18% for the three month periods ending September 30, 2010 and 2009, respectively.

Our cost of products sold (excluding any allocation of direct and indirect overhead and handling costs) for the nine month period ended 2010 increased by 3% to $74,000 from $72,000 for the same period in 2009. Our cost of products sold (excluding any allocation of direct and indirect overhead and handling costs) as a percentage of sales was 14% and 16% for the nine month periods ending September 30, 2010 and 2009, respectively.

Historically, changes in both sales volume and product mix have a significant effect on our cost of sales and our margins. Our margins vary significantly among our products.  Our margins for the same product also vary based on quantity sold.  Our increased inventory of our more popular products provides some delay from increasing costs of materials.  The timing of when we receive, supply and ship complexes or large periodic orders has a significant effect on our quarterly and year to date cost of products sold (excluding any allocation of direct and indirect overhead and handling costs).

As we buy some of our inventory from foreign suppliers, the change in the value of the U.S. dollar in relation to the Euro and other foreign currencies does have an effect on our cost of inventory, and will continue to do so. We buy most of our products from outside the U.S. using U.S. dollars.  Our main supplier of fine chemicals and complexes, Cyclodextrin Research & Development Laboratory, is located in Hungary and its prices are set in Euros.  The cost of our bulk inventory often changes due to fluctuations in the U.S. dollar. These products represent a significant portion of our revenues.  When we experience short-term increases in currency fluctuation or supplier price increases, we are often not able to raise our prices sufficiently to maintain our historical margins and therefore, our margins on these sales may decline.

Personnel expenses have decreased by 9% to $103,000 for the three months ended September 30, 2010, from $114,000 for the same period in 2009. Personnel expenses have decreased by 8% to $282,000 for the nine months ended September 30, 2010, from $306,000 for same period in 2009. While we added a significant new position related to our new spray drying operation in January 2010, our personnel expense decreased due to certain personnel costs capitalized as facility improvements and changes in personnel staffing.

Professional fees increased by 113% to $35,000 for the three months ended September  30, 2010, compared to $17,000 for same period in 2009. Professional fees increased by 49% to $110,000 for the nine months ended September 30, 2010, compared to $74,000 for the same period in 2009. The increase for all periods is due to a change in legal counsel during the second quarter of 2010.

During 2009, we hired a consultant to perform certain public relations activities through April 1, 2010, for 2,200,000 shares of restricted common stock, which were issued in 2010.  We recorded an expense of $66,000 for the three months ended March 31, 2010.

Office and other expenses increased to $29,000 from $7,000 for the three months ended September 30, 2010, and 2009, respectively. Office and other expenses increased from $21,000 to $48,000 for the nine months ended September 30, 2010, and 2009, respectively. The increases for all periods is due to added indirect expenses of acquiring our new facility, indirect expenses of preparing our High Springs, Florida facility for sale, and indirect costs of building our spray dryer and related facility.  We expect our future office related expenses to increase from historical levels with the addition of our second facility.  Once our High Springs, Florida facility is sold, we expect our office related expenses to return to historical levels.

Amortization and depreciation were comparable at approximately $5,000 for the three months ended September 30, 2010 and 2009, respectively. Amortization and depreciation were comparable at approximately $15,000 for the nine months ended September 30, 2010, and 2009, respectively. We expect depreciation to increase in future periods as the result of our new spray dryer and our second facility and planned future property improvements.

10

Freight and shipping increased to $5,000 from $3,000 for the three months ended September 30, 2010 and 2009, respectively. Freight and shipping increased to $13,000 from $8,000 for the nine months ended September 30, 2010 and 2009, respectively. These increases are due to increased sales.  Freight and shipping costs are dependent on supplier location, frequency of ordering products for inventory and frequency of sales.  We have also experienced volatility in overall shipping costs due to increases in energy costs and then decreasing overall demand for shipping services.

Investment and other income decreased in 2010 due to lower invested cash balances in 2010 compared to 2009, due to our use of cash for building our spray drying facility.

We recognized net income (loss) before income taxes of ($18,000) and $33,000 for the three month periods ending September 30, 2010 and 2009, respectively. We recognized a net loss of ($87,000) and ($31,000) for the nine month periods ending September 30, 2010 and 2009, respectively.

We realized a net tax loss for the three and nine month periods ended September 30, 2010, and recorded an increase in our valuation allowance of $50,000 due to the expiration of a net operating loss carry forward in 2010, which reduced our deferred tax asset by $50,000.

We realized net taxable income for the three months ended September 30, 2009 and a net tax loss for the nine month periods ended September 30, 2009.  For the three months ended September 30, 2009, we recognized income tax expense of $9,000, recognized a benefit of our net operating loss  carryforward of $9,000, which reduced our deferred tax asset valuation allowance by $9,000. For the nine months ended September 30, 2009, we recorded an income tax benefit of $9,000 and also increased our deferred tax asset valuation allowance for $9,000.

Our goal is to continue to introduce new products that will increase sales revenue and implement a strategy of creating or acquiring operational affiliates and/or subsidiaries that will use cyclodextrins in herbal medicines, waste-water remediation, pharmaceuticals, and foods. We also intend to pursue exclusive relationships with major cyclodextrin manufacturer(s) and specialty cyclodextrin labs to distribute their products. We continue to be the exclusive distributor in place North America of the cyclodextrin products manufactured by Cyclodextrin Research & Development Laboratory in Budapest, Hungary. In keeping with our commitment to use the internet as a major advertising and public relations outlet, we continue to update and maintain our website. This valuable asset has been instrumental in creating and maintaining a worldwide leadership role for us in the implementation of research and commercialization of cyclodextrin applications.

Item 3.  Quantitative and Qualitative Disclosures About Market Risk.

Not applicable.

Items 4. Controls and Procedures.

a.  Evaluation of Disclosure Controls and Procedures.

Our management, with the participation of our principal executive and principal financial officer, has evaluated the effectiveness of our disclosure controls and procedures (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (the "Exchange Act")) as of the end of the period covered by this quarterly report (the "Evaluation Date"). Based on such evaluation, our principal executive and principal financial officer has concluded that, as of the Evaluation Date, our disclosure controls and procedures are effective.

b.  Changes in Internal Control.

We made no changes in our internal control over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) identified in connection with the evaluation of our internal controls that occurred during our last fiscal quarter that has materially affected, or which is reasonably likely to materially affect our internal control over financial reporting.

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Part II. OTHER INFORMATION

Item 6.  Exhibits.

EXHIBIT NO.	DESCRIPTION
31.1	Certification of Principal Executive and Principal Financial Officer pursuant to Exchange Act rule 13(a)-14(a) (under Section 302 of the Sarbanes-Oxley Act of 2002).
32.1	Certification of Principal Executive and Principal Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

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SIGNATURES

Pursuant to the requirements of the Exchange Act, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

	CTD HOLDINGS, INC
Date: February 2, 2011	/s/ C.E. Rick Strattan
	C.E. Rick Strattan
	Chief Executive Officer
	(principal executive, financial and accounting officer)

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