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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001181431-08-065700.txt : 20081205
<SEC-HEADER>0001181431-08-065700.hdr.sgml : 20081205
<ACCEPTANCE-DATETIME>20081205130708
ACCESSION NUMBER:		0001181431-08-065700
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080623
FILED AS OF DATE:		20081205
DATE AS OF CHANGE:		20081205

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LANGE LOUIS G
		CENTRAL INDEX KEY:			0001238401

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-21643
		FILM NUMBER:		081232034

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		6503848500

	MAIL ADDRESS:	
		STREET 1:		3172 PORTER DRIVE
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94034

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CV THERAPEUTICS INC
		CENTRAL INDEX KEY:			0000921506
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				431570294
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3172 PORTER DR
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		6503848500

	MAIL ADDRESS:	
		STREET 1:		3172 PORTER DRIVE
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd221369.xml
<DESCRIPTION>FORM 4 LOUIS G LANGE 092208 RSU DISTRIBUTION
<TEXT>
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                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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                <transactionShares>
                    <value>4453</value>
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                    <value>11.15</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
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                <sharesOwnedFollowingTransaction>
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                    <value>572</value>
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                <transactionAcquiredDisposedCode>
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                    <value>I</value>
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                <value>2009-12-22</value>
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                    <value>90467</value>
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                <transactionShares>
                    <value>1293</value>
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                <transactionPricePerShare>
                    <value>0</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
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            <exerciseDate>
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                <value>2009-12-22</value>
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                <underlyingSecurityTitle>
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                <sharesOwnedFollowingTransaction>
                    <value>11641</value>
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    <footnotes>
        <footnote id="F1">Includes 1,300 shares acquired May 16, 2008 and 787 shares acquired August 15, 2008 pursuant to the CV Therapeutics, Inc. Employee Stock Purchase Plan (&quot;ESPP&quot;).</footnote>
        <footnote id="F2">Shares held in the Reporting Person's name in the Issuer's 401(k) plan.</footnote>
        <footnote id="F3">Upon payout, the Reporting Person is entitled to receive 1 share of common stock for each 1 restricted stock unit.</footnote>
        <footnote id="F4">20,169 shares of this grant vested effective December 22, 2005; 5.554% of the shares of common stock subject to this grant shall vest at the end of each three month period (each a &quot;Vesting Date&quot;) commencing on December 22, 2005, such that 100% of the shares of common stock subject to the restricted stock units are vested on December 22, 2009. Shares of common stock subject to any restricted stock units that vest shall be distributed to the Reporting Person in whole shares of common stock on each twelve (12) month anniversary of their relevant Vesting Date.</footnote>
        <footnote id="F5">The shares subject to this grant commenced vesting as of December 22, 2005; 6.25% of the shares of common stock subject to this grant shall vest at the end of each three month period (each a &quot;Vesting Date&quot;) commencing on December 22, 2005, such that 100% of the shares of common stock subject to the restricted stock units are vested on December 22, 2009. Shares of common stock subject to any restricted stock units that vest shall be distributed to the Reporting Person in whole shares of common stock on each twelve (12) month anniversary of their relevant Vesting Date.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Tricia Borga Suvari, Attorney-in Fact for : Louis G. Lange</signatureName>
        <signatureDate>2008-12-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----