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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Operating activities:    
Net loss $ (23,155,000) $ (22,181,000)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Depreciation 1,169,000 1,114,000
Gain upon extinguishment of Paycheck Protection Program loan (722,000)  
Stock-based compensation 2,882,000 3,475,000
Non-cash interest expense 60,000 628,000
Payment of accreted interest for deferred consideration for asset acquisition (586,000) (432,000)
Changes in operating assets and liabilities:    
Award receivable (2,428,000) (467,000)
Accounts payable and accrued liabilities 184,000 544,000
Accrued compensation 472,000 (760,000)
Operating lease right-of-use asset and liability, net 499,000 803,000
Prepaid expenses and other current assets (1,950,000) (994,000)
Net cash used in operating activities (23,575,000) (18,270,000)
Investing activities:    
Purchases of property and equipment (1,304,000) (824,000)
Net cash used in investing activities (1,304,000) (824,000)
Financing activities:    
Principal payment of deferred consideration for asset acquisition (1,414,000) (568,000)
Proceeds from Paycheck Protection Program Loan   717,000
Proceeds from sale of common stock, net of offering costs 26,319,000 22,893,000
Proceeds from exercise of warrants and stock options 613,000 168,000
Net cash provided by financing activities 25,518,000 23,210,000
Net increase in cash, cash equivalents and restricted cash 639,000 4,116,000
Cash, cash equivalents and restricted cash, beginning of period 10,849,000 6,733,000
Cash, cash equivalents and restricted cash, end of period 11,488,000 10,849,000
Supplemental disclosure of cash flow information:    
ROU asset obtained by assuming operating lease liabilities 26,056,000  
Paycheck Protection Program loan forgiveness 722,000  
Unpaid offering costs 13,000 65,000
Property and equipment included in accounts payable $ 38,000 $ 150,000