Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Consolidated Statements of Operations [Abstract]
Grant revenue	$ 4,474,000	$ 823,000
Operating expenses
Research and development	20,015,000	14,444,000
General and administrative	8,281,000	7,966,000
Total operating expenses	28,296,000	22,410,000
Loss from operations	(23,822,000)	(21,587,000)
Other income (expense)
Gain upon extinguishment of Paycheck Protection Program loan	726,000
Interest income	5,000	28,000
Interest expense	(64,000)	(628,000)
Other income (expense)		6,000
Total other income (expense), net	667,000	(594,000)
Net loss	$ (23,155,000)	$ (22,181,000)
Per share information:
Net loss per share, basic	$ (0.96)	$ (1.35)
Weighted average shares outstanding, basic	24,104,146	16,415,012
Net loss per share, diluted	$ (0.96)	$ (1.35)
Weighted average shares outstanding, diluted	24,104,146	16,415,012