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Consolidated Statements of Operations - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Consolidated Statements of Operations [Abstract]    
Grant revenue $ 823,000  
Operating expenses    
Research and development 14,444,000 $ 9,824,000
General and administrative 7,966,000 9,265,000
Loss on sale of assets (Note 6)   663,000
Total operating expenses 22,410,000 19,752,000
Loss from operations (21,587,000) (19,752,000)
Other income (expense)    
Interest income 28,000 96,000
Interest expense (628,000) (931,000)
Other income (expense) 6,000 (9,000)
Change in fair value of derivative liabilities   1,117,000
Total other income (expense), net (594,000) 273,000
Net loss $ (22,181,000) $ (19,479,000)
Per share information:    
Net loss per share, basic $ (1.35) $ (2.49)
Weighted average shares outstanding, basic 16,415,012 7,827,197
Net loss per share, diluted $ (1.35) $ (2.55)
Weighted average shares outstanding, diluted 16,415,012 8,009,909