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Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Operating activities:    
Net loss $ (14,893,000) $ (15,601,000)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Acquired in-process research and development   5,691,000
Depreciation 1,049,000 1,139,000
Stock-based compensation 3,224,000 47,000
Non-cash interest expense 717,000 676,000
Change in fair value of derivative liability (1,117,000) 241,000
Amortization of premiums of available-for-sale securities   33,000
Changes in operating assets and liabilities:    
Accounts payable and accrued liabilities (1,171,000) 515,000
Accrued compensation (609,000)  
Deferred rent and lease liabilities, net (252,000) (216,000)
Prepaid expenses and other current assets 199,000 43,000
Net cash used in operating activities (12,853,000) (7,432,000)
Investing activities:    
Purchases of available-for-sale securities   (3,392,000)
Proceeds from sales and maturities of available-for-sale securities   13,016,000
Purchases of property and equipment (203,000) (484,000)
Proceeds from sale of property and equipment   209,000
Cash acquired in reverse merger transaction 3,008,000  
Net cash provided by investing activities 2,805,000 9,349,000
Financing activities:    
Payment of deferred consideration for asset acquisition (1,000,000)  
Proceeds from sale of common stock, net of offering costs 9,975,000  
Net cash provided by financing activities 8,975,000  
Net increase (decrease) in cash, cash equivalents and restricted cash (1,073,000) 1,917,000
Cash, cash equivalents and restricted cash, beginning of period 10,463,000 12,276,000
Cash, cash equivalents and restricted cash, end of period 9,390,000 $ 14,193,000
Supplemental schedule of non-cash financing activities:    
Issuance of common stock in reverse merger transaction 10,710,000  
Conversion of deferred asset acquisition consideration upon reverse merger $ 1,463,000