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Capital Stock and Warrants (Details) - AmpliPhi Biosciences Corporation [Member] - USD ($)
12 Months Ended
Oct. 16, 2018
Sep. 19, 2018
Mar. 22, 2018
Jan. 12, 2018
Sep. 19, 2017
May 10, 2017
Dec. 31, 2018
Dec. 31, 2017
Class of Stock [Line Items]                
Sale of stock, number of shares sold in transaction     2,743,640 4,000,000        
Sale of stock, price per share     $ 1.10 $ 1.00        
Proceeds from equity offerings, net     $ 2,800,000 $ 3,400,000     $ 12,248,000 $ 9,353,000
Proceeds from equity offerings, gross     $ 3,000,000 $ 4,000,000        
Value of common stock issued               $ 519,000
Common stock closing price             $ 0.21  
Warrants exercised             217,400 226,664
Proceeds from exercises of warrants             $ 198,000 $ 130,000
Warrants expired during period             28,331 17,683
Weighted Average [Member]                
Class of Stock [Line Items]                
Exercise price of warrants             $ 1.08  
Common Stock Issuance Agreement [Member]                
Class of Stock [Line Items]                
Capital raised limit for Price Protection Obligation             $ 10.0  
CSIA Second Issuance [Member]                
Class of Stock [Line Items]                
Shares issued per agreement   523,210            
Value of common stock issued         $ 519,000      
Common stock closing price         $ 0.99      
CSIA Second Issuance [Member] | General and administrative expense [Member]                
Class of Stock [Line Items]                
Charges related to common stock included in general and administrative expense               $ 519,000
Common Stock [Member]                
Class of Stock [Line Items]                
Shares issued per agreement               523,210
Value of common stock issued               $ 5,000
Public Offering of Warrants and Common Stock [Member]                
Class of Stock [Line Items]                
Sale of stock, number of shares sold in transaction 14,875,000         2,584,085    
Proceeds from equity offerings, net $ 5,800,000         $ 9,400,000    
Costs related to equity offerings           $ 1,200,000    
Public Offering of Warrants and Common Stock [Member] | Pre-Funded Warrant [Member]                
Class of Stock [Line Items]                
Number of securities called by warrants 2,125,000         4,483,334    
Sale of stock, price per share $ 0.39              
Number of shares called by each warrant 1         1    
Exercise price of warrants $ 0.01         $ 0.01    
Combined warrant and stock price per unit           $ 1.49    
Public Offering of Warrants and Common Stock [Member] | Common Warrant [Member]                
Class of Stock [Line Items]                
Number of securities called by warrants 17,500,000         8,000,000    
Sale of stock, price per share $ 0.40              
Exercise price of warrants $ 0.40         $ 1.50    
Expiration term of warrants, period following effective date of warrants 5 years         5 years    
Combined warrant and stock price per unit           $ 1.50