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Consolidated Statements of Cash Flows - USD ($)
6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Operating activities:    
Net loss $ (7,938,000) $ (12,830,000)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Acquired in-process research and development   5,691,000
Depreciation 683,000 802,000
Stock-based compensation 725,000 39,000
Non-cash interest expense 536,000 369,000
Change in fair value of derivative liability (1,117,000) 135,000
Amortization of premiums of available-for-sale securities   33,000
Loss on sale of property and equipment   145,000
Changes in operating assets and liabilities:    
Accounts payable and accrued expenses (599,000) (133,000)
Accrued compensation (351,000) 392,000
Deferred rent (168,000) (144,000)
Prepaid expenses and other current assets (57,000) 89,000
Net cash used in operating activities (8,286,000) (5,412,000)
Investing activities:    
Purchases of available-for-sale securities   (3,392,000)
Proceeds from sales and maturities of available-for-sale securities   13,016,000
Purchases of property and equipment (268,000) (329,000)
Proceeds from sale of property and equipment   65,000
Cash acquired in reverse merger transaction 3,008,000  
Net cash provided by investing activities 2,740,000 9,360,000
Financing activities:    
Payment of deferred consideration for asset acquisition (1,000,000)  
Proceeds from sale of common stock, net of offering costs 9,975,000  
Net cash provided by financing activities 8,975,000  
Net increase (decrease) in cash, cash equivalents and restricted cash 3,429,000 3,948,000
Cash, cash equivalents and restricted cash, beginning of period 10,463,000 12,276,000
Cash, cash equivalents and restricted cash, end of period 13,892,000 $ 16,224,000
Supplemental schedule of non-cash financing activities:    
Issuance of common stock in reverse merger transaction 10,710,000  
Conversion of deferred asset acquisition consideration upon reverse merger 1,462,000  
Property and equipment included in accounts payable $ 113,000