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Document And Entity Information - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2018
Mar. 08, 2019
Jun. 29, 2018
Document And Entity Information [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2018    
Document Fiscal Year Focus 2018    
Document Fiscal Period Focus FY    
Entity Registrant Name AmpliPhi Biosciences Corp    
Entity Central Index Key 0000921114    
Current Fiscal Year End Date --12-31    
Entity Filer Category Smaller Reporting Company    
Trading Symbol APHB    
Entity Current Reporting Status Yes    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Public Float     $ 18.6
Entity Common Stock, Shares Outstanding   32,294,008