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Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Operating activities:    
Net loss $ (7,790,000) $ (10,486,000)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Change in fair value of derivative liabilities 46,000 (1,997,000)
Stock-based compensation 366,000 568,000
Charge for common stock issuance (Note 6)   519,000
Depreciation 268,000 255,000
Amortization of patents 23,000 23,000
Other non-cash adjustments, net   22,000
Impairment charges   5,800,000
Deferred taxes   (1,302,000)
Changes in operating assets and liabilities:    
Accounts payable and accrued expenses 218,000 (595,000)
Prepaid expenses and other current assets (85,000) 370,000
Net cash used in operating activities (6,954,000) (6,823,000)
Investing activities:    
Purchases of property and equipment (41,000) (40,000)
Net cash used in investing activities (41,000) (40,000)
Financing activities:    
Proceeds from sale of common stock and related warrants, net of offering costs 6,159,000 9,353,000
Proceeds from exercises of warrants 198,000 31,000
Proceeds from stock issuance under employee stock purchase plan 5,000 3,000
Principal payments on note payable   (510,000)
Net cash provided by financing activities 6,362,000 8,877,000
Net increase (decrease) in cash and cash equivalents (633,000) 2,014,000
Cash and cash equivalents, beginning of period 5,132,000 5,711,000
Cash and cash equivalents, end of period 4,499,000 $ 7,725,000
Supplemental schedule of non-cash financing activities:    
Offering costs included in accounts payable $ 277,000