<SEC-DOCUMENT>0001144204-18-049744-index.html : 20180918
<SEC-HEADER>0001144204-18-049744.hdr.sgml : 20180918
<ACCEPTANCE-DATETIME>20180918083300
ACCESSION NUMBER:		0001144204-18-049744
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		12
FILED AS OF DATE:		20180918
DATE AS OF CHANGE:		20180918

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AmpliPhi Biosciences Corp
		CENTRAL INDEX KEY:			0000921114
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				911549568
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-226959
		FILM NUMBER:		181074687

	BUSINESS ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		804-827-2524

	MAIL ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGETED GENETICS CORP /WA/
		DATE OF NAME CHANGE:	19940331
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>tv501500_s1a.htm
<DESCRIPTION>AMENDMENT NO. 1 TO FORM S-1
<TEXT>
Document 1 - file: tv501500_s1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.1
<SEQUENCE>2
<FILENAME>tv501500_ex1-1.htm
<DESCRIPTION>EXHIBIT 1.1
<TEXT>
Document 2 - file: tv501500_ex1-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.18
<SEQUENCE>3
<FILENAME>tv501500_ex4-18.htm
<DESCRIPTION>EXHIBIT 4.18
<TEXT>
Document 3 - file: tv501500_ex4-18.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>tv501500_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 4 - file: tv501500_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>5
<FILENAME>tv501500_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 5 - file: tv501500_ex23-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>lg_ampliphi.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: lg_ampliphi.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tv501500_ex5-1img1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tv501500_ex5-1img1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>tv501500_slide1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: tv501500_slide1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>tv501500_slide2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: tv501500_slide2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>tv501500_slide3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: tv501500_slide3.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>tv501500_slide4.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: tv501500_slide4.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>tv501500_slide5.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: tv501500_slide5.jpg

</DOCUMENT>
</SEC-DOCUMENT>