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Consolidated Statements of Cash Flows - USD ($)
6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Operating activities:    
Net loss $ (6,184,000) $ (9,707,000)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Change in fair value of derivative liabilities 77,000 (2,034,000)
Impairment charges   5,800,000
Stock-based compensation 246,000 470,000
Deferred taxes   (1,302,000)
Depreciation 178,000 170,000
Amortization of patents 15,000 15,000
Other non-cash adjustments, net   18,000
Changes in operating assets and liabilities:    
Accounts payable and accrued expenses 28,000 (12,000)
Prepaid expenses and other current assets (69,000) 352,000
Net cash used in operating activities (5,709,000) (6,230,000)
Investing activities:    
Purchases of property and equipment (31,000) (7,000)
Net cash used in investing activities (31,000) (7,000)
Financing activities:    
Proceeds from sale of common stock and related warrants, net of offering costs 6,203,000 9,690,000
Proceeds from exercises of warrants 198,000  
Proceeds from stock issuance under employee stock purchase plan 5,000 3,000
Principal payment on note payable   (205,000)
Net cash provided by financing activities 6,406,000 9,488,000
Net increase in cash and cash equivalents 666,000 3,251,000
Cash and cash equivalents, beginning of period 5,132,000 5,711,000
Cash and cash equivalents, end of period 5,798,000 8,962,000
Supplemental schedule of non-cash financing activities:    
Offering costs included in accounts payable $ 44,000 $ 339,000