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Consolidated Statements of Operations - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Consolidated Statement of Operations [Abstract]    
Revenue   $ 29,000
Operating expenses    
Research and development (benefit) $ 1,464,000 1,490,000
General and administrative 1,591,000 1,898,000
Total operating expenses 3,055,000 3,388,000
Loss from operations (3,055,000) (3,359,000)
Other income (expense)    
Change in fair value of derivative liabilities (79,000) 114,000
Other expense, net   (1,000)
Total other income (expense), net (79,000) 113,000
Net loss (3,134,000) (3,246,000)
Net loss attributable to common stockholders $ (3,134,000) $ (3,246,000)
Per share information:    
Net loss per share, basic and diluted $ (0.24) $ (1.94)
Weighted average shares outstanding, basic and diluted 13,298,159 1,677,497