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Fair Value of Financial Assets and Liabilities - Derivative Instruments (Valuation Assumptions Used for November 2016 Offering Warrants) (Details) - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Common stock closing price $ 4.30  
November 2016 Warrant Derivative Liability [Member]    
Volatility 112.00% 112.00%
Expected term (years) 4 years 7 months 21 days 4 years 10 months 21 days
Risk-free interest rate 1.85% 1.91%
Dividend yield 0.00% 0.00%
Exercise price [1] $ 7.50 $ 7.50
Common stock closing price $ 4.30 $ 4.40
[1] (1) The exercise price of the November 2016 offering warrants will be adjusted downward due to events subsequent to March 31, 2017 (see Note 8).