Income Taxes (Components of Deferred Tax Assets) (Details) - USD ($)	Dec. 31, 2016	Dec. 31, 2015
Income Taxes [Abstract]
Net operating loss carry-forwards	$ 67,479,000	$ 65,425,000
Research and orphan drug credit carry-forwards	3,109,000	5,181,000
Depreciation and amortization	4,000	(3,000)
Stock options and other	1,010,000	479,000
Intangible Assets	(2,367,000)	(3,079,000)
Deferred Tax Assets, Gross, Total	69,235,000	68,003,000
Valuation allowance for deferred tax assets	(71,684,000)	(71,008,000)
Deferred Tax Assets, Net, Total	$ (2,449,000)	$ (3,005,000)