<SEC-DOCUMENT>0001144204-16-123796-index.html : 20160914
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<ACCEPTANCE-DATETIME>20160913214131
ACCESSION NUMBER:		0001144204-16-123796
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		10
FILED AS OF DATE:		20160914
DATE AS OF CHANGE:		20160913

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AmpliPhi Biosciences Corp
		CENTRAL INDEX KEY:			0000921114
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				911549568
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-213421
		FILM NUMBER:		161884056

	BUSINESS ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		804-827-2524

	MAIL ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGETED GENETICS CORP /WA/
		DATE OF NAME CHANGE:	19940331
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<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>v448721_s1a.htm
<DESCRIPTION>S-1/A
<TEXT>
Document 1 - file: v448721_s1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.1
<SEQUENCE>2
<FILENAME>v448721_ex1-1.htm
<DESCRIPTION>EXHIBIT 1.1
<TEXT>
Document 2 - file: v448721_ex1-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.17
<SEQUENCE>3
<FILENAME>v448721_ex4-17.htm
<DESCRIPTION>EXHIBIT 4.17
<TEXT>
Document 3 - file: v448721_ex4-17.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>v448721_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 4 - file: v448721_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>5
<FILENAME>v448721_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 5 - file: v448721_ex23-1.htm

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<SEQUENCE>6
<FILENAME>tex5-1logo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: tex5-1logo.jpg

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<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>line.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: line.gif

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<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>spacer.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: spacer.gif

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>logo_ampliphi.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: logo_ampliphi.jpg

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<TYPE>GRAPHIC
<SEQUENCE>10
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<TEXT>
Document 10 - file: v448195_img-lcb.jpg

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