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Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($)
Redeemable Convertible Preferred Stock Series B [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Total
Balances at Dec. 31, 2014 $ 1,990,000 $ 40,000 $ 365,403,000 $ (362,006,000) $ 3,437,000
Balances (in shares) at Dec. 31, 2014 8,671,040 3,983,182      
Net loss       (516,000) (516,000)
Accretion of dividends on Series B redeemable convertible preferred stock $ 1,307,000   (1,307,000)   (1,307,000)
Accretion to redemption value of Series B redeemable convertible stock 8,971,000   (8,971,000)   (8,971,000)
Conversion of Series B redeemable convertible preferred stock to common stock, value $ (378,000) $ 2,000 1,504,000   1,506,000
Conversion of Series B redeemable convertible preferred stock to common stock, shares (1,143,187) 228,637      
Common stock issued in financing, net of offering costs and warrants   $ 16,000 8,250,000   8,266,000
Common stock issued in financing, net of offering costs and warrants (shares)   1,575,758      
Warrants exercised   $ 1,000 1,072,000   1,073,000
Warrants exercised (in shares)   56,645      
Warrants reclassified from liabilities to equity due to amendment of warrants     5,462,000   5,462,000
Warrants reclassified from liabilities to equity due to increase in authorized shares     3,281,000   3,281,000
Exercise of common stock options and other (in shares)   39,281      
Stock-based compensation     479,000   479,000
Stock-based compensation - severance     4,000   4,000
Balances at Dec. 31, 2015 $ 11,890,000 $ 59,000 375,177,000 (362,522,000) 12,714,000
Balances (in shares) at Dec. 31, 2015 7,527,853 5,883,503      
Net loss       (6,963,000) (6,963,000)
Accretion of dividends on Series B redeemable convertible preferred stock $ 365,000   (365,000)   (365,000)
Accretion to redemption value of Series B redeemable convertible stock 1,493,000   (1,493,000)   (1,493,000)
Warrants issued for Novolytics assets (value)     204,000   204,000
Conversion of Series B redeemable convertible preferred stock to common stock, value $ (13,748,000) $ 24,000 11,820,000   11,844,000
Conversion of Series B redeemable convertible preferred stock to common stock, shares (7,527,853) 2,359,025      
Common stock issued in financing, net of offering costs and warrants   $ 21,000 2,613,000   $ 2,634,000
Common stock issued in financing, net of offering costs and warrants (shares)   2,127,660      
Exercise of common stock options and other (in shares)        
Common stock issued pursuant to anti-dilution rights   $ 7,000 1,538,000   $ 1,545,000
Common stock issued pursuant to anti-dilution rights (shares)   750,206      
Stock-based compensation     1,364,000   1,364,000
Balances at Jun. 30, 2016   $ 111,000 $ 390,858,000 $ (369,485,000) $ 21,484,000
Balances (in shares) at Jun. 30, 2016   11,120,394