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Consolidated Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash flows from operating activities    
Net loss $ (3,112,000) $ (14,493,000)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Change in fair value of warrant liability (4,000) 4,690,000
Change in fair value of Series B preferred stock derivative liability (1,402,000) 7,105,000
Warrants issued 204,000 213,000
Amortization of patents 8,000 8,000
Depreciation 73,000 58,000
Stock-based compensation 816,000 52,000
Changes in operating assets and liabilities: [Abstract]    
Accounts receivable 111,000 100,000
Accounts payable, accrued expenses, deferred revenue and other 436,000 158,000
Accrued severance (170,000) (122,000)
Prepaid expenses and other current assets (45,000) (74,000)
Net cash used in operating activities (3,085,000) (2,305,000)
Investing activities:    
Purchases of property and equipment (112,000) (35,000)
Net cash used in investing activities (112,000) (35,000)
Financing activities:    
Proceeds from issuance of common stock, net   12,384,000
Net cash provided by financing activities   12,384,000
Net (decrease) increase in cash and cash equivalents (3,197,000) 10,044,000
Cash and cash equivalents, beginning of period 9,370,000 6,581,000
Cash and cash equivalents, end of period 6,173,000 16,625,000
Supplemental schedule of non-cash financing activities:    
Accretion of Series B redeemable convertible preferred stock $ 1,725,000 338,000
Fair value of warrant liability upon issuance   $ 4,211,000