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Warrants (Narrative) (Details)
1 Months Ended 3 Months Ended 4 Months Ended 12 Months Ended
Aug. 03, 2015
USD ($)
shares
Apr. 29, 2015
USD ($)
shares
Apr. 01, 2015
USD ($)
shares
Mar. 16, 2015
USD ($)
$ / shares
shares
Dec. 31, 2013
$ / shares
shares
Jul. 15, 2013
USD ($)
$ / shares
shares
Mar. 31, 2015
USD ($)
May. 31, 2013
$ / shares
shares
Dec. 31, 2015
USD ($)
$ / shares
shares
Dec. 31, 2014
USD ($)
shares
Aug. 02, 2015
shares
May. 08, 2015
USD ($)
Dec. 22, 2011
$ / shares
shares
Class of Warrant or Right [Line Items]                          
Sale of stock, price per share | $ / shares                 $ 3.98        
Warrant expiration date               February through May 2018          
Warrant liability                 $ 6,000 $ 5,826,000      
Amount reclassified from warrant liability into equity $ 3,281,000 $ 46,000 $ 630,000                 $ 5,462,000  
Reverse stock split, description 1-for-50 (1:50) reverse stock split of its common stock, par value $0.01 per share                        
Conversion ratio of reverse stock split 50                        
Common stock, shares authorized | shares 670,000,000               670,000,000 670,000,000 445,000,000    
Fair value of liquidated damages reclassified to shareholders' equity $ 120,000                        
Gain (loss) on remeasurement of fair value of warrant liability                 $ 610,000 $ 9,455,000      
Warrant issuance expense                 (213,000)        
Series March 2015 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Number of securities called by warrants | shares       393,939                  
Exercise price of warrants | $ / shares       $ 10.75                  
Series B Placement - June 26, 2013 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Warrant liability           $ 4,285,000              
Warrants exercised | shares   4,525 52,120                    
Shares issued upon exercise of warrants | shares   4,525 52,120                    
Series B Placement - July 15, 2013 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Warrant liability           $ 674,000              
Placement Agent [Member]                          
Class of Warrant or Right [Line Items]                          
Warrant liability       $ 814,000                  
Other expenses related to issuance of warrants             $ 213,000   $ 218,000        
Down Round Position [Member]                          
Class of Warrant or Right [Line Items]                          
Exercise price of warrants | $ / shares       $ 8.25                  
Biocontrol Business Combination [Member]                          
Class of Warrant or Right [Line Items]                          
Number of securities called by warrants | shares                         27,103
Exercise price of warrants | $ / shares                         $ 23.00
Warrant expiration date                 December 2016        
Convertible Notes Payable [Member]                          
Class of Warrant or Right [Line Items]                          
Number of securities called by warrants | shares               140,608          
Exercise price of warrants | $ / shares               $ 7.00          
Private Placement [Member]                          
Class of Warrant or Right [Line Items]                          
Sale of stock, number of shares issued in transaction | shares       1,575,758 1,440,140                
Sale of stock, price per share | $ / shares       $ 8.25 $ 12.50                
Warrant liability       $ 4,210,000                  
Other expenses related to issuance of warrants       $ 213,000                  
Private Placement [Member] | Series March 2015 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Exercise price of warrants | $ / shares       $ 10.75                  
Warrant expiration date       March 2020                  
Warrant liquidation charges if warrants not exercised according to terms       $ 2,500,000                  
Warrant liability       $ 3,396,000                  
Private Placement [Member] | Series December 2013 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Number of securities called by warrants | shares         86,408                
Exercise price of warrants | $ / shares         $ 12.50                
Warrant expiration date         December 2018                
Private Placement [Member] | Placement Agent [Member]                          
Class of Warrant or Right [Line Items]                          
Number of securities called by warrants | shares       94,545                  
Exercise price of warrants | $ / shares       $ 10.75                  
Private Placement - Series B Preferred Stock [Member]                          
Class of Warrant or Right [Line Items]                          
Number of securities called by warrants | shares           600,805              
Exercise price of warrants | $ / shares           $ 7.00              
Private Placement - Series B Preferred Stock [Member] | Series B Placement - June 26, 2013 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Warrant expiration date           June 2018              
Private Placement - Series B Preferred Stock [Member] | Series B Placement - July 15, 2013 Warrants [Member]                          
Class of Warrant or Right [Line Items]                          
Warrant expiration date           July 2018              
Private Placement - Series B Preferred Stock [Member] | Placement Agent [Member]                          
Class of Warrant or Right [Line Items]                          
Warrant issuance expense           $ 759,000