Income Taxes (Components of Deferred Tax Assets) (Details) - USD ($)	Dec. 31, 2015	Dec. 31, 2014
Income Taxes [Abstract]
Net operating loss carry-forwards	$ 65,425,000	$ 61,332,000
Research and orphan drug credit carry-forwards	5,181,000	3,855,000
Depreciation and amortization	(3,000)	(8,000)
Stock options and other	479,000	1,381,000
Intangible Assets	(3,079,000)	(3,155,000)
Deferred Tax Assets, Gross, Total	68,003,000	63,405,000
Valuation allowance for deferred tax assets	(71,008,000)	(66,483,000)
Deferred Tax Assets, Net, Total	$ (3,005,000)	$ (3,078,000)