Stock-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2015

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

Stock-based compensation expense recognized was as follows:

	Three Months Ended March 31,
	2015		2014
	(Unaudited)		(Unaudited)
Research and development expense	$	29,000	$	38,000
General and administrative expense		23,000		196,000
Total stock-based compensation expense	$	52,000	$	234,000

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

The following table summarizes stock option activity for the three months ended March 31, 2015:

			Options Outstanding
	Shares				Weighted Average		Average Remaining
	Available for				Exercise		Contractual Term		Intrinsic
	Grant		Shares		Price		(Years)		Value
Balance, December 31, 2014		39,250,000		22,034,747	$	0.19		8.18	$	640,837
Granted		—		—		—		—		—
Exercised		—		—		—		—		—
Forfeited		—		—		—		—		—
Expired		—		—		—		—		—
Balance, March 31, 2015		39,250,000		22,034,747	$	0.19		7.93	$	2,561,000
Vested or expected to vest at March 31, 2015				21,890,939	$	0.19		7.92	$	2,547,000
Exercisable at March 31, 2015				19,995,058	$	0.18		7.92	$	2,396,000

Schedule of Common Stock, Capital Shares Reserved for Future Issuance [Table Text Block]

As of March 31, 2015, the Company had reserved shares of its common stock for future issuance as follows:

	Shares Reserved
Stock options outstanding		22,034,747
Available for future grants under the Stock Incentive Plan		39,250,000
Warrants		63,314,696
Total Shares reserved		124,599,443