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Consolidated Balance Sheets (USD $)
Sep. 30, 2014
Dec. 31, 2013
Current assets    
Cash and cash equivalents $ 9,786,000us-gaap_CashAndCashEquivalentsAtCarryingValue $ 20,355,000us-gaap_CashAndCashEquivalentsAtCarryingValue
Accounts receivable 27,000us-gaap_AccountsReceivableNetCurrent 8,000us-gaap_AccountsReceivableNetCurrent
Prepaid expenses and other current assets 448,000us-gaap_PrepaidExpenseAndOtherAssetsCurrent 297,000us-gaap_PrepaidExpenseAndOtherAssetsCurrent
Total current assets 10,261,000us-gaap_AssetsCurrent 20,660,000us-gaap_AssetsCurrent
Property and equipment, net of accumulated depreciation of $559,000 and $473,000 as of September 30, 2014 and December 31, 2013, respectively 1,283,000us-gaap_PropertyPlantAndEquipmentNet 145,000us-gaap_PropertyPlantAndEquipmentNet
Intangible assets    
In process research and development 12,446,000us-gaap_IntangibleAssetsNetExcludingGoodwill 12,446,000us-gaap_IntangibleAssetsNetExcludingGoodwill
Patents, net of accumulated amortization of $116,000 and $93,000 as of September 30, 2014 and December 31, 2013, respectively 377,000us-gaap_FiniteLivedPatentsGross 400,000us-gaap_FiniteLivedPatentsGross
Goodwill 7,562,000us-gaap_Goodwill 7,562,000us-gaap_Goodwill
Total intangible assets 20,385,000us-gaap_IntangibleAssetsNetIncludingGoodwill 20,408,000us-gaap_IntangibleAssetsNetIncludingGoodwill
Total assets 31,929,000us-gaap_Assets 41,213,000us-gaap_Assets
Current liabilities    
Accounts payable and accrued expenses 1,840,000us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent 2,147,000us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent
Deferred revenue 246,000us-gaap_DeferredRevenueCurrent 244,000us-gaap_DeferredRevenueCurrent
Accrued severance 449,000us-gaap_EmployeeRelatedLiabilitiesCurrent 0us-gaap_EmployeeRelatedLiabilitiesCurrent
Total current liabilities 2,535,000us-gaap_LiabilitiesCurrent 2,391,000us-gaap_LiabilitiesCurrent
Long term liabilities    
Derivative preferred shares conversion liability 14,043,000aphb_DerivativePreferredSharesConversionLiability 40,791,000aphb_DerivativePreferredSharesConversionLiability
Derivative warrants liability 6,035,000aphb_DerivativeWarrantsLiability 16,871,000aphb_DerivativeWarrantsLiability
Deferred tax liability 3,078,000us-gaap_DeferredTaxLiabilitiesNoncurrent 3,078,000us-gaap_DeferredTaxLiabilitiesNoncurrent
Accrued severance 210,000aphb_EmployeeRelatedLiabilitiesNonCurrent 0aphb_EmployeeRelatedLiabilitiesNonCurrent
Total long term liabilities 23,366,000us-gaap_LiabilitiesNoncurrent 60,740,000us-gaap_LiabilitiesNoncurrent
Total liabilities 25,901,000us-gaap_Liabilities 63,131,000us-gaap_Liabilities
Series B redeemable convertible preferred stock $0.01 par value, 10,000,000 shares authorized, 8,859,978 shares issued and outstanding at December 31, 2013 (liquidation preference of $13,712,000 and 13,022,000 at September 30, 2014 and December 31, 2014, respectively) 1,660,000us-gaap_TemporaryEquityCarryingAmountAttributableToParent 707,000us-gaap_TemporaryEquityCarryingAmountAttributableToParent
Stockholders' equity (deficit)    
Common stock, $0.01 par value, 445,000,000 shares authorized, 187,159,093 shares issued and outstanding at September 30, 2014 and 182,535,562 shares issued and outstanding at December 31, 2013 1,872,000us-gaap_CommonStockValue 1,825,000us-gaap_CommonStockValue
Additional paid-in capital 362,001,000us-gaap_AdditionalPaidInCapital 358,828,000us-gaap_AdditionalPaidInCapital
Paid-in-capital - contingent shares 1,837,000us-gaap_OtherAdditionalCapital 1,837,000us-gaap_OtherAdditionalCapital
Accumulated deficit (361,342,000)us-gaap_RetainedEarningsAccumulatedDeficit (385,115,000)us-gaap_RetainedEarningsAccumulatedDeficit
Total stockholders' equity (deficit) 4,368,000us-gaap_StockholdersEquity (22,625,000)us-gaap_StockholdersEquity
Total liabilities, Series B redeemable convertible preferred stock and stockholders' equity (deficit) $ 31,929,000us-gaap_LiabilitiesAndStockholdersEquity $ 41,213,000us-gaap_LiabilitiesAndStockholdersEquity