Stock Options (Tables)

9 Months Ended

Sep. 30, 2014

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

Following is a summary of the amount included as stock-based compensation expense in the accompanying consolidated statements of operations:

	Three Months Ended				Nine Months Ended
	September		September		September		September
	30, 2014		30, 2013		30, 2014		30, 2013
Income statement category:
Research and development	$	38,000	$	40,000	$	116,000	$	153,000
General and administrative		209,000		208,000		598,000		1,053,000
Severance charge		1,161,000		—		1,161,000		—
Total stock-based compensation expense	$	1,408,000	$	248,000	$	1,875,000	$	1,206,000

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

      The following table summarizes Option activity:

				Average Remaining
			Weighted Average	Contractual Term
	Shares		Exercise Price	(Years)		Intrinsic Value
Outstanding at December 31, 2013	25,721,000	$	0.19	9.15	$	6,451,441
Granted	—		—
Exercised	—		—
Forfeited	3,137,378		0.19
Expired	2,000		13.10
Outstanding at September 30, 2014	22,581,622	$	0.19	2.15	$	862,982
Exercisable at September 30, 2014	19,972,558	$	0.19	1.35	$	822,989

Schedule of Common Stock, Capital Shares Reserved for Future Issuance [Table Text Block]

As of September 30, 2014, the Company had reserved shares of its common stock for future issuance as follows:

	Shares Reserved
Stock options outstanding	22,581,622
Available for future grants under the 2013 Stock Incentive Plan	39,250,000
Warrants	38,890,451
Total shares reserved	100,722,073