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Consolidated Statement of Cash Flows (USD $)
3 Months Ended 12 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Dec. 31, 2013
Cash flows from operating activities      
Net loss from operations $ (11,307,000)us-gaap_NetIncomeLoss $ (1,645,000)us-gaap_NetIncomeLoss $ (64,583,000)us-gaap_NetIncomeLoss
Adjustments required to reconcile net loss from operations to net cash used in operating activities:      
Loss on derivative liabilities 8,773,000us-gaap_DerivativeGainLossOnDerivativeNet (87,000)us-gaap_DerivativeGainLossOnDerivativeNet 49,330,000us-gaap_DerivativeGainLossOnDerivativeNet
Shares issued for technology access fee 0us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims 0us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims 3,000,000us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims
Amortization of note discount and patents 8,000us-gaap_AdjustmentForAmortization 311,000us-gaap_AdjustmentForAmortization 2,667,000us-gaap_AdjustmentForAmortization
Warrants issued as investment fees 0aphb_FairvalueOfWarrantsIssuedAsInvestmentFees 0aphb_FairvalueOfWarrantsIssuedAsInvestmentFees 759,000aphb_FairvalueOfWarrantsIssuedAsInvestmentFees
Depreciation 18,000us-gaap_Depreciation 21,000us-gaap_Depreciation 82,000us-gaap_Depreciation
Stock-based compensation 234,000us-gaap_ShareBasedCompensation 154,000us-gaap_ShareBasedCompensation 1,437,000us-gaap_ShareBasedCompensation
Changes in operating assets and liabilities net of acquisitions:      
Accounts receivable (4,000)us-gaap_IncreaseDecreaseInAccountsReceivable 12,000us-gaap_IncreaseDecreaseInAccountsReceivable 15,000us-gaap_IncreaseDecreaseInAccountsReceivable
Tax refund 0us-gaap_IncreaseDecreaseInIncomeTaxesReceivable 618,000us-gaap_IncreaseDecreaseInIncomeTaxesReceivable 618,000us-gaap_IncreaseDecreaseInIncomeTaxesReceivable
Accounts payable and accrued expenses (1,365,000)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities (380,000)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities 454,000us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Prepaid expenses and other current assets (48,000)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets (219,000)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets (149,000)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Interest on loan notes 0us-gaap_IncreaseDecreaseInInterestPayableNet 96,000us-gaap_IncreaseDecreaseInInterestPayableNet 233,000us-gaap_IncreaseDecreaseInInterestPayableNet
Other 0us-gaap_OtherOperatingActivitiesCashFlowStatement 0us-gaap_OtherOperatingActivitiesCashFlowStatement (155,000)us-gaap_OtherOperatingActivitiesCashFlowStatement
Net cash used in operating activities (3,691,000)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations (1,119,000)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations (6,292,000)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities      
Purchases of property and equipment (229,000)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment 0us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (102,000)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Net cash used in investing activities (229,000)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations 0us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations (102,000)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities      
Proceeds from December financings 0us-gaap_ProceedsFromIssuanceOfCommonStock 0us-gaap_ProceedsFromIssuanceOfCommonStock 16,887,000us-gaap_ProceedsFromIssuanceOfCommonStock
Proceeds from Series B redeemable convertible preferred stock 0us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock 0us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock 7,000,000us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock
Proceeds from convertible loan notes 0us-gaap_ProceedsFromConvertibleDebt 976,000us-gaap_ProceedsFromConvertibleDebt 2,000,000us-gaap_ProceedsFromConvertibleDebt
Net cash provided by financing activities 0us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 976,000us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 25,887,000us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Net increase (decrease) in cash and cash equivalents (3,920,000)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease (143,000)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 19,493,000us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents, beginning of period 20,355,000us-gaap_CashAndCashEquivalentsAtCarryingValue 862,000us-gaap_CashAndCashEquivalentsAtCarryingValue 862,000us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of period 16,435,000us-gaap_CashAndCashEquivalentsAtCarryingValue 719,000us-gaap_CashAndCashEquivalentsAtCarryingValue 20,355,000us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental schedule of non-cash financing activities:      
Conversion of convertible loan notes and accrued interest to Series B redeemable convertible preferred stock 0us-gaap_DebtConversionConvertedInstrumentAmount1 0us-gaap_DebtConversionConvertedInstrumentAmount1 6,316,000us-gaap_DebtConversionConvertedInstrumentAmount1
Accretion of Series B redeemable convertible preferred stock $ 314,000aphb_AccretionOfSeriesBRedeemableConvertiblePreferredStock $ 0aphb_AccretionOfSeriesBRedeemableConvertiblePreferredStock $ 618,000aphb_AccretionOfSeriesBRedeemableConvertiblePreferredStock