Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit) (USD $)	Total	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Redeemable Convertible Preferred Stock Series B [Member]
Balances at Dec. 31, 2012	$ 12,943,000	$ 669,000	$ 332,806,000	$ (320,532,000)	$ 0
Balances (in shares) at Dec. 31, 2012		66,908,810			0
Net loss	(64,583,000)	0	0	(64,583,000)	0
Stock-based compensation	1,437,000	0	1,437,000	0	0
Beneficial conversion feature and warrants associated with issuance of convertible loan notes	2,635,000	0	2,635,000	0	0
Shares issued for Intrexon	3,000,000	240,000	2,760,000	0	0
Shares issued for Intrexon (in shares)		24,000,000			0
Accretion of Series B convertible preferred stock to its redemption value	(618,000)	0	(618,000)	0	618,000
Issuance of preferred stock from conversion of convertible loan notes	0	0	0	0	50,000
Issuance of preferred stock from conversion of convertible loan notes (in shares)		0			5,016,081
Issuance of preferred stock	0	0	0	0	50,000
Issuance of preferred stock (in shares)		0			4,999,999
Preferred shares converted to common stock	7,084,000	115,000	6,969,000	0	(11,000)
Preferred shares converted to common stock (in shares)		11,561,020			(1,156,102)
Stock options exercised	13,000	1,000	12,000	0	0
Stock options exercised (in shares)		61,018			0
Shares released from escrow	0	80,000	(80,000)	0	0
Shares released from escrow (in shares)		8,000,000			0
Issuance of common stock for December financing	15,464,000	720,000	14,744,000	0	0
Issuance of common stock for December financing (in shares)		72,007,000			0
Escheat shares	0	0	0	0	0
Escheat shares (in shares)		(2,286)			0
Balances at Dec. 31, 2013	(22,625,000)	1,825,000	360,665,000	(385,115,000)	707,000
Balances (in shares) at Dec. 31, 2013		182,535,562			8,859,978
Net loss	(11,307,000)	0	0	(11,307,000)	0
Stock-based compensation	234,000	0	234,000	0	0
Accretion of Series B convertible preferred stock to its redemption value	(314,000)	0	(314,000)	0	314,000
Balances at Mar. 31, 2014	$ (34,012,000)	$ 1,825,000	$ 360,585,000	$ (396,422,000)	$ 1,021,000
Balances (in shares) at Mar. 31, 2014		182,535,562			8,859,978