<SEC-DOCUMENT>0001144204-15-000474-index.html : 20150105
<SEC-HEADER>0001144204-15-000474.hdr.sgml : 20150105
<ACCEPTANCE-DATETIME>20150105164252
ACCESSION NUMBER:		0001144204-15-000474
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		9
FILED AS OF DATE:		20150105
DATE AS OF CHANGE:		20150105

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AmpliPhi Biosciences Corp
		CENTRAL INDEX KEY:			0000921114
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				911549568
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-193458
		FILM NUMBER:		15505588

	BUSINESS ADDRESS:	
		STREET 1:		4870 SADLER ROAD
		STREET 2:		SUITE 300
		CITY:			GLEN ALLEN
		STATE:			VA
		ZIP:			23060
		BUSINESS PHONE:		650-888-2422

	MAIL ADDRESS:	
		STREET 1:		4870 SADLER ROAD
		STREET 2:		SUITE 300
		CITY:			GLEN ALLEN
		STATE:			VA
		ZIP:			23060

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGETED GENETICS CORP /WA/
		DATE OF NAME CHANGE:	19940331
</SEC-HEADER>
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<TYPE>424B3
<SEQUENCE>1
<FILENAME>v398030_424b3.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: v398030_424b3.htm

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<TEXT>
Document 2 - file: logo_ampliphi-biocorp2.jpg

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<DOCUMENT>
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<SEQUENCE>3
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<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: spacer.gif

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>line.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: line.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>v367027_img-mice.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: v367027_img-mice.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>v367027_chrt-line.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: v367027_chrt-line.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>v365643_chrt-scatter1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: v365643_chrt-scatter1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>v365643_chrt-scatter2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: v365643_chrt-scatter2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>v365643_img-lifecycle.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: v365643_img-lifecycle.jpg

</DOCUMENT>
</SEC-DOCUMENT>