Consolidated Statements of Stockholders' Equity (Deficit) (USD $)	Total	Preferred Stock [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Accumulated Other Comprehensive Income (Loss) [Member]
Balances at Dec. 31, 2012	$ 12,943,000	$ 0	$ 669,000	$ 332,806,000	$ (320,426,000)	$ (106,000)
Balances (in shares) at Dec. 31, 2012		0	66,908,810
Net loss	(57,648,000)	0	0	0	(57,648,000)	0
Stock-based compensation	1,437,000	0	0	1,437,000	0	0
Beneficial conversion feature and warrants associated with issuance of convertible loan notes	2,635,000	0	0	2,635,000	0	0
Shares issued for Intrexon	3,000,000	0	240,000	2,760,000	0	0
Shares issued for Intrexon (in shares)		0	24,000,000
Issuance of preferred stock from conversion of convertible loan notes	50,000	50,000	0	0	0	0
Issuance of preferred stock from conversion of convertible loan notes (in shares)		5,016,081	0
Issuance of preferred stock	50,000	50,000	0	0	0	0
Issuance of preferred stock (in shares)		4,999,999	0
Preferred stock converted to common stock	6,615,000	(11,000)	115,000	6,511,000	0	0
Preferred stock converted to common stock (in shares)		(1,156,102)	11,561,020
Stock options exercised	13,000	0	1,000	12,000	0	0
Stock options exercised (in shares)		0	61,018
Shares released from escrow	0	0	80,000	(80,000)	0	0
Shares released from escrow (in shares)		0	8,000,000
Issuance of common stock for December financing	15,464,000	0	720,000	14,744,000	0	0
Issuance of common stock for December financing (in shares)		0	72,007,000
Escheat shares		0	(2,286)
Foreign currency translations	41,000	0	0	0	0	41,000
Balances at Dec. 31, 2013	(15,400,000)	89,000	1,825,000	360,825,000	(378,074,000)	(65,000)
Balances (in shares) at Dec. 31, 2013		8,859,978	182,535,562
Net loss	(12,029,000)	0	0	0	(12,029,000)	0
Stock-based compensation	262,000	0	0	262,000	0	0
Foreign currency translations	(4,000)	0	0	0	0	(4,000)
Balances at Mar. 31, 2014	$ (27,171,000)	$ 89,000	$ 1,825,000	$ 361,087,000	$ (390,103,000)	$ (69,000)
Balances (in shares) at Mar. 31, 2014		8,859,978	182,535,562