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Stock-Based Compensation (Details) (USD $)
3 Months Ended 12 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Dec. 31, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense $ 262,000 $ 154,000 $ 1,437,000
Research and development expense [Member]
     
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense 38,000 42,000 191,000
General and administrative expense [Member]
     
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense $ 224,000 $ 112,000 $ 1,246,000