EXHIBIT 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in the Registration Statements on Form S-3 (Nos. 333-144495, 333-140187, 333-116600, 333-107822, 333-74976, 333-50214, 333-33192, 333-86509, 333-51625) of Targeted Genetics Corporation and in the related Prospectus and to the incorporation by reference in the Registration Statements on Form S-8 (Nos. 333-143604, 333-116601, 333-61738, 333-48220, 333-78523, 333-58907, 333-28151, 333-03889) pertaining to the Targeted Genetics Corporation’s Stock Incentive Plan, 1992 Restated Stock Option Plan, 1999 Stock Option Plan, and 2000 Genovo Roll-over Stock Option Plan, and Stock Option Plan for Nonemployee Directors of our report dated March 20, 2008, with respect to the consolidated financial statements Targeted Genetics Corporation included in the Annual Report (Form 10-K) for the year ended December 31, 2007.

	/s/ Ernst & Young LLP
Seattle, Washington March 20, 2008